Reduced physiologically-based pharmacokinetic model of repaglinide: impact of OATP1B1 and CYP2C8 genotype and source of in vitro data on the prediction of drug-drug interaction risk.

Reduced physiologically-based pharmacokinetic model of repaglinide: impact of OATP1B1 and CYP2C8 genotype and source of in vitro data on the prediction of drug-drug interaction risk.

Item
http://www.wikidata.org/entity/Q30776360
Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationA variation in KCNQ1 gene is associated with repaglinide efficacy on insulin resistance in Chinese Type 2 Diabetes Mellitus Patients.The Promises of Quantitative Proteomics in Precision MedicinePrediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved.Dealing with the complex drug-drug interactions: towards mechanistic models.Incorporation of stochastic variability in mechanistic population pharmacokinetic models: handling the physiological constraints using normal transformations.Intracellular Unbound Atorvastatin Concentrations in the Presence of Metabolism and Transport.Development and Application of a Mechanistic Pharmacokinetic Model for Simvastatin and its Active Metabolite Simvastatin Acid Using an Integrated Population PBPK Approach.Effect of Chronic Kidney Disease on Nonrenal Elimination Pathways: A Systematic Assessment of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and OATP.Gaining mechanistic insight into coproporphyrin I as endogenous biomarker for OATP1B-mediated drug-drug interactions using population pharmacokinetic modelling and simulation.Role of Hepatic Drug Transporters in Drug Development.
P2860

Reduced physiologically-based pharmacokinetic model of repaglinide: impact of OATP1B1 and CYP2C8 genotype and source of in vitro data on the prediction of drug-drug interaction risk.

Item
http://www.wikidata.org/entity/Q30776360
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Reduced physiologically-based ...... of drug-drug interaction risk.
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Reduced physiologically-based ...... of drug-drug interaction risk.
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type
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Reduced physiologically-based ...... of drug-drug interaction risk.
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Reduced physiologically-based ...... of drug-drug interaction risk.
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Reduced physiologically-based ...... of drug-drug interaction risk.
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Reduced physiologically-based ...... of drug-drug interaction risk.
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Reduced physiologically-based ...... of drug-drug interaction risk
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P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921