Molecular basis of APC/C regulation by the spindle assembly checkpoint.
about
UBE2C induces EMT through Wnt/β‑catenin and PI3K/Akt signaling pathways by regulating phosphorylation levels of Aurora-A.Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex.The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C.Phylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpoint.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.Delayed APC/C activation extends the first mitosis of mouse embryos.Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer propertiesSlip slidin' away of mitosis with CRL2Zyg11.Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C.Basis of catalytic assembly of the mitotic checkpoint complex.Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint ArrestA sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing.Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C).Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.The PP2AB56 phosphatase promotes the association of Cdc20 with APC/C in mitosis.Meiotic spindle formation in mammalian oocytes: Implications for human infertility.Role of ubiquitylation of components of mitotic checkpoint complex in their dissociation from anaphase-promoting complex/cyclosome.Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.Sumoylation promotes optimal APC/C Activation and Timely Anaphase.Cell division: Mitotic regulation comes into focus.USP9X Limits Mitotic Checkpoint Complex Turnover to Strengthen the Spindle Assembly Checkpoint and Guard against Chromosomal Instability.Peptide inhibitors of the anaphase promoting-complex that cause sensitivity to microtubule poison.MAD1: Kinetochore Receptors and Catalytic Mechanisms.TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCCImplications of alternative routes to APC/C inhibition by the mitotic checkpoint complexMechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
P2860
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P2860
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
description
2016 nî lūn-bûn
@nan
2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
@ast
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
@en
type
label
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
@ast
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
@en
prefLabel
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
@ast
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
@en
P2093
P2860
P356
P1433
P1476
Molecular basis of APC/C regulation by the spindle assembly checkpoint.
@en
P2093
Claudio Alfieri
David Barford
Leifu Chang
Mark Skehel
Sarah Maslen
P2860
P2888
P304
P356
10.1038/NATURE19083
P407
P577
2016-08-10T00:00:00Z