Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
about
MtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage.Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism.Mathematical modeling of the role of mitochondrial fusion and fission in mitochondrial DNA maintenance.A random mutation capture assay to detect genomic point mutations in mouse tissueAre mutagenic non D-loop direct repeat motifs in mitochondrial DNA under a negative selection pressure?Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA MutationsSignaling and Damaging Functions of Free Radicals in Aging-Free Radical Theory, Hormesis, and TOR.Maximizing signal-to-noise ratio in the random mutation capture assayEvolution of Cell-to-Cell Variability in Stochastic, Controlled, Heteroplasmic mtDNA Populations.The systems biology of mitochondrial fission and fusion and implications for disease and aging.Is mitochondrial DNA turnover slower than commonly assumed?The effect of dichloroacetate on health- and lifespan in C. elegans.
P2860
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P2860
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
@ast
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
@en
type
label
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
@ast
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
@en
prefLabel
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
@ast
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
@en
P2093
P2860
P1476
Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico
@en
P2093
Barry Halliwell
Jan Gruber
Suresh Kumar Poovathingal
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000572
P577
2009-11-20T00:00:00Z