Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues.
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Changes in the transcriptional profile of transporters in the intestine along the anterior-posterior and crypt-villus axesPredicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical ModelsAn update on renal peptide transporters.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Cross-species comparison of genes related to nutrient sensing mechanisms expressed along the intestine.Significance and regional dependency of peptide transporter (PEPT) 1 in the intestinal permeability of glycylsarcosine: in situ single-pass perfusion studies in wild-type and Pept1 knockout micePeptide transporter 1 is responsible for intestinal uptake of the dipeptide glycylsarcosine: studies in everted jejunal rings from wild-type and Pept1 null miceEffect of dose escalation on the in vivo oral absorption and disposition of glycylsarcosine in wild-type and Pept1 knockout mice.Influence of fed-fasted state on intestinal PEPT1 expression and in vivo pharmacokinetics of glycylsarcosine in wild-type and Pept1 knockout mice.Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications.Functional and molecular expression of the proton-coupled oligopeptide transporters in spleen and macrophages from mouse and humanTHE EVALUATION OF PEPTIDE/HISTIDINE TRANSPORTER 1 (PHT1) FUNCTION: UPTAKE KINETICS UTILIZING A COS-7 STABLY TRANSFECTED CELL LINESimulations of the nonlinear dose dependence for substrates of influx and efflux transporters in the human intestineImpact of intestinal PepT1 on the kinetics and dynamics of N-formyl-methionyl-leucyl-phenylalanine, a bacterially-produced chemotactic peptide.Urea nitrogen salvage mechanisms and their relevance to ruminants, non-ruminants and man.Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestineDi- and tripeptide transport in vertebrates: the contribution of teleost fish models.Circumvention of P-gp and MRP2 mediated efflux of lopinavir by a histidine based dipeptide prodrug.Orally active antiviral tripeptide glycyl-prolyl-glycinamide is activated by CD26 (dipeptidyl peptidase IV) before transport across the intestinal epithelium.Function and expression of the proton-coupled amino acid transporter PAT1 along the rat gastrointestinal tract: implications for intestinal absorption of gaboxadol.Investigation of oral bioavailability and brain distribution of the Ind(8)-Val conjugate of indinavir in rodents.S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes.Impact of a high-cholesterol diet on expression levels of Niemann-Pick C1-like 1 and intestinal transporters in rats and mice.Expression and regulation of proton-coupled oligopeptide transporters in colonic tissue and immune cells of mice.Semi-Mechanistic Population Pharmacokinetic Modeling of L-Histidine Disposition and Brain Uptake in Wildtype and Pht1 Null Mice.Current knowledge of intestinal absorption of bioactive peptides.Evaluating Human Intestinal Cell Lines for Studying Dietary Protein Absorption.Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Future
P2860
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P2860
Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Spatial expression patterns of ...... l, and multiple human tissues.
@ast
Spatial expression patterns of ...... l, and multiple human tissues.
@en
type
label
Spatial expression patterns of ...... l, and multiple human tissues.
@ast
Spatial expression patterns of ...... l, and multiple human tissues.
@en
prefLabel
Spatial expression patterns of ...... l, and multiple human tissues.
@ast
Spatial expression patterns of ...... l, and multiple human tissues.
@en
P2093
P2860
P356
P1433
P1476
Spatial expression patterns of ...... l, and multiple human tissues.
@en
P2093
D Herrera-Ruiz
O S Gudmundsson
P2860
P356
10.1208/PS030109
P577
2001-01-01T00:00:00Z