Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations.
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Fuzziness: linking regulation to protein dynamicsGaussian-weighted RMSD superposition of proteins: a structural comparison for flexible proteins and predicted protein structures.Scale-free flow of life: on the biology, economics, and physics of the cellCrystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5Targeting G protein coupled receptor-related pathways as emerging molecular therapiesPrinciples of allosteric interactions in cell signalingRegulating highly dynamic unstructured proteins and their coding mRNAsBinding of small molecules to an adaptive protein-protein interfaceStructure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndromeEnzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selectionCrystal packing modifies ligand binding affinity: The case of aldose reductaseStandardization and quality control in quantifying non-enzymatic oxidative protein modifications in relation to ageing and disease: Why is it important and why is it hard?Comparing neural-network scoring functions and the state of the art: applications to common library screeningConformational transitions upon ligand binding: holo-structure prediction from apo conformationsA role for both conformational selection and induced fit in ligand binding by the LAO proteinCollective dynamics differentiates functional divergence in protein evolutionIn silico assessment of potential druggable pockets on the surface of α1-antitrypsin conformersQuantitatively characterizing the ligand binding mechanisms of choline binding protein using Markov state model analysisDistribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discoveryDiverse flavonoids stimulate NodD1 binding to nod gene promoters in Sinorhizobium meliloti.The role of dynamic conformational ensembles in biomolecular recognitionSmall-molecule inhibitors of protein-protein interactions: progressing towards the dreamPyrone-Based Inhibitors of Metalloproteinase Types 2 and 3 May Work as Conformation-Selective InhibitorsAdaptability in protein structures: structural dynamics and implications in ligand design.Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.Molecular Characterization and Computational Modelling of New Delhi Metallo-β-Lactamase-5 from an Escherichia coli Isolate (KOEC3) of Bovine Origin.Mapping molecular flexibility of proteins with site-directed spin labeling: a case study of myoglobin.Structural and dynamic determinants of protein-peptide recognition.Atomic force microscopy: a multifaceted tool to study membrane proteins and their interactions with ligands.Segmented transition pathway of the signaling protein nitrogen regulatory protein CBinary image representation of a ligand binding site: its application to efficient sampling of a conformational ensembleTrapping of peptide-based surrogates in an artificially created channel of cytochrome c peroxidase.A new, structurally nonredundant, diverse data set of protein-protein interfaces and its implicationsConformational diversity and computational enzyme designAntibody evolution constrains conformational heterogeneity by tailoring protein dynamics.Binding induced conformational changes of proteins correlate with their intrinsic fluctuations: a case study of antibodies.Binding-induced folding of a natively unstructured transcription factor.Two-state allosteric modeling suggests protein equilibrium as an integral component for cyclic AMP (cAMP) specificity in the cAMP receptor protein of Escherichia coli.Database of ligand-induced domain movements in enzymesMolecular dynamics simulation of phosphorylated KID post-translational modification.
P2860
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P2860
Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Multiple diverse ligands bindi ...... r of pre-existing populations.
@ast
Multiple diverse ligands bindi ...... r of pre-existing populations.
@en
type
label
Multiple diverse ligands bindi ...... r of pre-existing populations.
@ast
Multiple diverse ligands bindi ...... r of pre-existing populations.
@en
prefLabel
Multiple diverse ligands bindi ...... r of pre-existing populations.
@ast
Multiple diverse ligands bindi ...... r of pre-existing populations.
@en
P2860
P50
P356
P1433
P1476
Multiple diverse ligands bindi ...... r of pre-existing populations.
@en
P2093
Haim J Wolfson
P2860
P304
P356
10.1110/PS.21302
P577
2002-02-01T00:00:00Z