An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease.
about
Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKRNaturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanismMolecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionPro-Apoptotic Kinase Levels in Cerebrospinal Fluid as Potential Future Biomarkers in Alzheimer's DiseaseThe role of mTOR signaling in Alzheimer diseasemTOR-dependent signalling in Alzheimer's diseaseSatratoxin G-induced apoptosis in PC-12 neuronal cells is mediated by PKR and caspase independentActivation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neuronsResistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKRThe small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alphaEndoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus facesIdentification of metastasis-related genes in a mouse model using a library of randomized ribozymes.Gene discovery by ribozyme and siRNA libraries.Human Herpesvirus 6A Exhibits Restrictive Propagation with Limited Activation of the Protein Kinase R-eIF2α Stress Pathway.Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in miceInhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity.The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease.Inhibition of host translation by virus infection in vivo.Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.Viruses, endoplasmic reticulum stress, and interferon responses.Significance of molecular signaling for protein translation control in neurodegenerative diseases.Hot topics in aging research: protein translation and TOR signaling, 2010Japanese encephalitis virus co-opts the ER-stress response protein GRP78 for viral infectivity.A chemical compound commonly used to inhibit PKR, {8-(imidazol-4-ylmethylene)-6H-azolidino[5,4-g] benzothiazol-7-one}, protects neurons by inhibiting cyclin-dependent kinase.Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase.Ethanol promotes endoplasmic reticulum stress-induced neuronal death: involvement of oxidative stress.Inhibition of PKR impairs angiogenesis through a VEGF pathway.Implication of protein kinase R gene quantification in hepatitis C virus genotype 4 induced hepatocarcinogenesis.Catalytic nucleic acid enzymes for the study and development of therapies in the central nervous system: Review Article.Translational control in synaptic plasticity and cognitive dysfunctionRecent advances in the molecular pathogenesis of dystonia-plus syndromes and heredodegenerative dystonias.Binding and relocalization of protein kinase R by murine cytomegalovirus.Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2.PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's diseaseTargeting ASK1 in ER stress-related neurodegenerative diseases.Rapamycin inhibits lipopolysaccharide-induced neuroinflammation in vitro and in vivo.The functional role of stress proteins in ER stress mediated cell death.The unfolded protein response in Alzheimer's disease.
P2860
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P2860
An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
An RNA-dependent protein kinas ...... tosis and Alzheimer's disease.
@ast
An RNA-dependent protein kinas ...... tosis and Alzheimer's disease.
@en
type
label
An RNA-dependent protein kinas ...... tosis and Alzheimer's disease.
@ast
An RNA-dependent protein kinas ...... tosis and Alzheimer's disease.
@en
prefLabel
An RNA-dependent protein kinas ...... tosis and Alzheimer's disease.
@ast
An RNA-dependent protein kinas ...... tosis and Alzheimer's disease.
@en
P2093
P2860
P356
P1433
P1476
An RNA-dependent protein kinas ...... tosis and Alzheimer's disease.
@en
P2093
Eigo Suyama
Hiroaki Kawasaki
Kazunari Taira
Masaya Tohyama
Reiko Onuki
Tadashi Baba
Taiichi Katayama
Yoshio Bando
P2860
P304
P356
10.1038/SJ.EMBOJ.7600049
P407
P577
2004-02-05T00:00:00Z