Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein.
about
Intrinsically disordered proteins are potential drug targetsGuiTope: an application for mapping random-sequence peptides to protein sequencesSelective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell linesThe catalytic Tyr-9 of glutathione S-transferase A1-1 controls the dynamics of the C terminusPhagotopes derived by antibody screening of phage-displayed random peptide libraries vary in immunoreactivity: studies using an exemplary monoclonal antibody, CII-C1, to type II collagen.Phage-displayed peptides bind to the malarial protein apical membrane antigen-1 and inhibit the merozoite invasion of host erythrocytes.Binding of urokinase plasminogen activator to gp130 via a putative urokinase-binding consensus sequence.Development of a peptide-mediated capture PCR for detection of Mycobacterium avium subsp. paratuberculosis in milk.Convergent evolution with combinatorial peptides.Genome-wide characterisation of the binding repertoire of small molecule drugs.Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism.A phase I pharmacokinetic and pharmacodynamic correlative study of the antisense Bcl-2 oligonucleotide g3139, in combination with carboplatin and paclitaxel, in patients with advanced solid tumors.Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesBCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.Paclitaxel accelerates spontaneous calcium oscillations in cardiomyocytes by interacting with NCS-1 and the InsP3RUse of phage display technology for the determination of the targets for small-molecule therapeutics.Target identification for small bioactive molecules: finding the needle in the haystack.Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets.Enhancing in vitro selection techniques to assist the discovery, understanding and use of inorganic binding peptides.Development of Next-Generation Peptide Binders Using In vitro Display Technologies and Their Potential Applications.Mitochondria as a target for inducing death of malignant hematopoietic cells.Mitochondrial abnormality in sensory, but not motor, axons in paclitaxel-evoked painful peripheral neuropathy in the rat.Biomathematical description of synthetic peptide libraries.Utilizing Yeast Surface Human Proteome Display Libraries to Identify Small Molecule-Protein Interactions.Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation.Microtubule drugs: action, selectivity, and resistance across the kingdoms of life.Mitochondria: pharmacological manipulation of cell deathHeat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide.Bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription.Conformational analysis of the carboxy-terminal tails of human beta-tubulin isotypes.Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.Paclitaxel: a review of adverse toxicities and novel delivery strategies.Enhancement of paclitaxel-induced breast cancer cell death via the glycogen synthase kinase-3β-mediated B-cell lymphoma 2 regulationMicrotubule stabilising agents for cancer chemotherapy.Structural studies of taxol analogues for drug discovery.BamHI-A rightward frame 1, an Epstein-Barr virus-encoded oncogene and immune modulator.Mechanisms of distal axonal degeneration in peripheral neuropathies.Paclitaxel and TRAIL synergize to kill paclitaxel-resistant small cell lung cancer cells through a caspase-independent mechanism mediated through AIF.Taxol directly induces endoplasmic reticulum-associated calcium changes that promote apoptosis in breast cancer cells.
P2860
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P2860
Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Screening of a library of phag ...... -2 as a taxol-binding protein.
@ast
Screening of a library of phag ...... -2 as a taxol-binding protein.
@en
type
label
Screening of a library of phag ...... -2 as a taxol-binding protein.
@ast
Screening of a library of phag ...... -2 as a taxol-binding protein.
@en
prefLabel
Screening of a library of phag ...... -2 as a taxol-binding protein.
@ast
Screening of a library of phag ...... -2 as a taxol-binding protein.
@en
P2093
P356
P1476
Screening of a library of phag ...... -2 as a taxol-binding protein.
@en
P2093
P304
P356
10.1006/JMBI.1998.2303
P577
1999-01-01T00:00:00Z