Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism. - Test2 - elhamkhani - TriplyDB

Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism.

Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism.

http://www.wikidata.org/entity/Q33264052

about

Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorder Multiple roles for frequenin/NCS-1 in synaptic function and development Simvastatin Sodium Salt and Fluvastatin Interact with Human Gap Junction Gamma-3 Protein Neuronal Calcium Sensor 1 Has Two Variants with Distinct Calcium Binding Characteristics Structural diversity of neuronal calcium sensor proteins and insights for activation of retinal guanylyl cyclase by GCAP1.Discrete proteolysis of neuronal calcium sensor-1 (NCS-1) by mu-calpain disrupts calcium binding.Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy.Paclitaxel accelerates spontaneous calcium oscillations in cardiomyocytes by interacting with NCS-1 and the InsP3R Use of phage display technology for the determination of the targets for small-molecule therapeutics.Increased spinal cord Na⁺-K⁺-2Cl⁻ cotransporter-1 (NKCC1) activity contributes to impairment of synaptic inhibition in paclitaxel-induced neuropathic pain Salinomycin induces calpain and cytochrome c-mediated neuronal cell death.Protection of neuronal calcium sensor 1 protein in cells treated with paclitaxel Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation.Prolonged oxaliplatin exposure alters intracellular calcium signaling: a new mechanism to explain oxaliplatin-associated peripheral neuropathy.Prevention of paclitaxel-induced peripheral neuropathy by lithium pretreatment.Inhibition of paclitaxel-induced decreases in calcium signaling.Using activation status of signaling pathways as mechanism-based biomarkers to predict drug sensitivity The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma Nerve growth factor alters microtubule targeting agent-induced neurotransmitter release but not MTA-induced neurite retraction in sensory neurons.Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology Microtubule stabilising agents for cancer chemotherapy.Inositol 1,4,5-trisphosphate receptor subtype-specific regulation of calcium oscillations.Antineoplastic drug-induced bradyarrhythmias.Mechanisms of distal axonal degeneration in peripheral neuropathies.WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response.Identifying the cellular targets of natural products using T7 phage display.Paclitaxel alters the evoked release of calcitonin gene-related peptide from rat sensory neurons in culture.Rising intracellular zinc by membrane depolarization and glucose in insulin-secreting clonal HIT-T15 beta cells.Taxol directly induces endoplasmic reticulum-associated calcium changes that promote apoptosis in breast cancer cells.A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.A novel preventive therapy for paclitaxel-induced cognitive deficits: preclinical evidence from C57BL/6 mice.Calcium Sensor, NCS-1, Promotes Tumor Aggressiveness and Predicts Patient Survival.Neurotoxic mechanisms of paclitaxel are local to the distal axon and independent of transport defects.The prevention of chemotherapy induced peripheral neuropathy by concurrent treatment with drugs used for bipolar disease: a retrospective chart analysis in human cancer patients.An assessment of neuronal calcium sensor-1 and response to neoadjuvant chemotherapy in breast cancer patients.

P2860

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P2860

Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism.

http://www.wikidata.org/entity/Q33264052

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2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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Paclitaxel induces calcium osc ...... sensor 1-dependent mechanism.

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Paclitaxel induces calcium osc ...... sensor 1-dependent mechanism.

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Paclitaxel induces calcium osc ...... sensor 1-dependent mechanism.

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Proceedings of the National Academy of Sciences of the United States of America

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Paclitaxel induces calcium osc ...... sensor 1-dependent mechanism.

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Barbara E Ehrlich

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David G Johnston

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David J Austin

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Ute Splittgerber

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P2860

Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1)

Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site

Neuronal calcium sensor-1 enhancement of InsP3 receptor activity is inhibited by therapeutic levels of lithium

Cyclosporin A-insensitive permeability transition in brain mitochondria: inhibition by 2-aminoethoxydiphenyl borate

The neuronal calcium sensor family of Ca2+-binding proteins

Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein.

Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation.

Two-dimensional diversity: screening human cDNA phage display libraries with a random diversity probe for the display cloning of phosphotyrosine binding domains.

Simultaneous identification of multiple protein targets by using complementary-DNA phage display and a natural-product-mimetic probe.

Molecular effects of paclitaxel: myths and reality (a critical review).

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