about
Microbial enzymes: tools for biotechnological processesTo get what we aim for--progress in diversity generation methodsEngineering non-heme mono- and dioxygenases for biocatalysisMutations of an NAD(P)H-dependent flavoprotein monooxygenase that influence cofactor promiscuity and enantioselectivityEnhanced Enzyme Kinetic Stability by Increasing Rigidity within the Active SiteEngineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnelPrecision is essential for efficient catalysis in an evolved Kemp eliminaseDirected divergent evolution of a thermostable D-tagatose epimerase towards improved activity for two hexose substratesDirected evolution of artificial metalloenzymes for in vivo metathesisThermostabilization of an esterase by alignment-guided focussed directed evolutionDNA polymerases engineered by directed evolution to incorporate non-standard nucleotidesProtein engineering by random mutagenesis and structure-guided consensus of Geobacillus stearothermophilus Lipase T6 for enhanced stability in methanolOmniChange: the sequence independent method for simultaneous site-saturation of five codonsComparison of the frequency of functional SH3 domains with different limited sets of amino acids using mRNA display.HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering.Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks.Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis.Engineering next generation proteases.Comparative characterization of random-sequence proteins consisting of 5, 12, and 20 kinds of amino acids.New efficient recombinant expression system to engineer Candida antarctica lipase B.Variants of a Thermus aquaticus DNA polymerase with increased selectivity for applications in allele- and methylation-specific amplification.PCRless library mutagenesis via oligonucleotide recombination in yeastConstruction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid.Revisiting the lipase from Pseudomonas aeruginosa: directed evolution of substrate acceptance and enantioselectivity using iterative saturation mutagenesis.Manipulating the expression rate and enantioselectivity of an epoxide hydrolase by using directed evolution.Optimization of combinatorial mutagenesis.When second best is good enough: another probabilistic look at saturation mutagenesis.Combinatorial reshaping of the Candida antarctica lipase A substrate pocket for enantioselectivity using an extremely condensed library.Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm.Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima.Structural insights from random mutagenesis of Campylobacter jejuni oligosaccharyltransferase PglB.Improving the thermostability of alpha-amylase by combinatorial coevolving-site saturation mutagenesis.Directed evolution by using iterative saturation mutagenesis based on multiresidue sites.Computational tools for rational protein engineering of aldolases.SwiftLib: rapid degenerate-codon-library optimization through dynamic programmingImprovement of biocatalysts for industrial and environmental purposes by saturation mutagenesisA high security double lock and key mechanism in HUH relaxases controls oriT-processing for plasmid conjugation.Engineering of a CPC acylase using a facile pH indicator assay.Combining rational and random strategies in β-glucosidase Zm-p60.1 protein library constructionGenetically enhanced lysozyme evades a pathogen derived inhibitory protein.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Addressing the numbers problem in directed evolution.
@ast
Addressing the numbers problem in directed evolution.
@en
type
label
Addressing the numbers problem in directed evolution.
@ast
Addressing the numbers problem in directed evolution.
@en
prefLabel
Addressing the numbers problem in directed evolution.
@ast
Addressing the numbers problem in directed evolution.
@en
P2093
P356
P1433
P1476
Addressing the numbers problem in directed evolution.
@en
P2093
Daniel Kahakeaw
Manfred T Reetz
Renate Lohmer
P304
P356
10.1002/CBIC.200800298
P577
2008-07-01T00:00:00Z