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ChannelopathiesTherapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug DiscoveryRegulation of transient receptor potential channels by the phospholipase C pathwayMscS-like mechanosensitive channels in plants and microbesCartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related OsteoarthritisTRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P₂Mechanical dynamics in live cells and fluorescence-based force/tension sensorsGain-of-function mutation in TRPV4 identified in patients with osteonecrosis of the femoral headTransient receptor potential (TRP) channels: a clinical perspectiveTRP channels in lower urinary tract dysfunction.Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations.Patient-derived skeletal dysplasia induced pluripotent stem cells display abnormal chondrogenic marker expression and regulation by BMP2 and TGFβ1Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cellsSwelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and gliaDeciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron.TRPV4 as a therapeutic target for joint diseases.L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel.Phosphorylation on TRPV4 Serine 824 Regulates Interaction with STIM1.Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells.A channelopathy mechanism revealed by direct calmodulin activation of TrpV4.Detection of TRPV4 channel current-like activity in Fawn Hooded hypertensive (FHH) rat cerebral arterial muscle cellsTRPV4 associates environmental temperature and sex determination in the American alligatorUnraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias.Activation of TRPV4 Regulates Respiration through Indirect Activation of Bronchopulmonary Sensory Neurons.Novel mutations highlight the key role of the ankyrin repeat domain in TRPV4-mediated neuropathy.Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome.Phosphoinositide signaling in somatosensory neuronsDiscrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension.High-resolution views of TRPV1 and their implications for the TRP channel superfamily.A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open.PNPLA6 mutations cause Boucher-Neuhauser and Gordon Holmes syndromes as part of a broad neurodegenerative spectrum.TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice.TRPV3: a 'more than skinny' channel.Calcium-permeable ion channels in pain signaling.Environmental temperature impact on bone and cartilage growth.The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements.Phosphoinositide regulation of TRP channelsSensory TRP channels: the key transducers of nociception and pain.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The puzzle of TRPV4 channelopathies.
@ast
The puzzle of TRPV4 channelopathies.
@en
type
label
The puzzle of TRPV4 channelopathies.
@ast
The puzzle of TRPV4 channelopathies.
@en
prefLabel
The puzzle of TRPV4 channelopathies.
@ast
The puzzle of TRPV4 channelopathies.
@en
P2860
P356
P1433
P1476
The puzzle of TRPV4 channelopathies.
@en
P2860
P304
P356
10.1038/EMBOR.2012.219
P577
2013-01-11T00:00:00Z