Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome.
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Thrombotic microangiopathy with targeted cancer agentsCancer-associated thrombotic microangiopathyActivation of cell stress response pathways by Shiga toxinsIdentification of small molecules that suppress ricin-induced stress-activated signaling pathwaysRed Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia.Ricin A-chain requires c-Jun N-terminal kinase to induce apoptosis in nontransformed epithelial cells.Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model.Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody.Proteomic study of differential protein expression in mouse lung tissues after aerosolized ricin poisoning.Production of IL-1β by bone marrow-derived macrophages in response to chemotherapeutic drugs: synergistic effects of doxorubicin and vincristine.Ricin Toxin Activates the NALP3 Inflammasome.Pokeweed antiviral protein increases HIV-1 particle infectivity by activating the cellular mitogen activated protein kinase pathway.A computational perspective of molecular interactions through virtual screening, pharmacokinetic and dynamic prediction on ribosome toxin A chain and inhibitors of Ricinus communis.Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signalingIntrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage.Evidence for widespread epithelial damage and coincident production of monocyte chemotactic protein 1 in a murine model of intestinal ricin intoxicationRole of apoptotic signaling pathways in regulation of inflammatory responses to ricin in primary murine macrophagesDiverse profiles of ricin-cell interactions in the lung following intranasal exposure to ricin.Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1.Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin.Activation of the cholinergic antiinflammatory pathway reduces ricin-induced mortality and organ failure in mice.A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response.Pathology of lethal and sublethal doses of aerosolized ricin in rhesus macaques.Protective effects of anti-ricin A-chain RNA aptamer against ricin toxicity.Ribosomal alteration-derived signals for cytokine induction in mucosal and systemic inflammation: noncanonical pathways by ribosomal inactivation.A novel swine model of ricin-induced acute respiratory distress syndromeThe interactions of human neutrophils with shiga toxins and related plant toxins: danger or safety?The immunomodulatory effects of lactic acid bacteria for improving immune functions and benefits.Chemical warfare agent and biological toxin-induced pulmonary toxicity: could stem cells provide potential therapies?Proinflammatory responses of human airway cells to ricin involve stress-activated protein kinases and NF-kappaB.Structure-based affinity maturation of a chimeric anti-ricin antibody C4C13.Morphological changes of ricin toxin-induced apoptosis in human cervical cancer cells.Plant ribosome-inactivating proteins type II induce the unfolded protein response in human cancer cells.Oropharyngeal aspiration of ricin as a lung challenge model for evaluation of the therapeutic index of antibodies against ricin A-chain for post-exposure treatment.Novel chimeric anti-ricin antibody C4C13 with neutralizing activity against ricin toxicity.Antibody/doxycycline combined therapy for pulmonary ricinosis: Attenuation of inflammation improves survival of ricin-intoxicated mice.Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages.TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death
P2860
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P2860
Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Administration of ricin induce ...... of hemolytic uremic syndrome.
@ast
Administration of ricin induce ...... of hemolytic uremic syndrome.
@en
type
label
Administration of ricin induce ...... of hemolytic uremic syndrome.
@ast
Administration of ricin induce ...... of hemolytic uremic syndrome.
@en
prefLabel
Administration of ricin induce ...... of hemolytic uremic syndrome.
@ast
Administration of ricin induce ...... of hemolytic uremic syndrome.
@en
P2093
P2860
P1476
Administration of ricin induce ...... of hemolytic uremic syndrome.
@en
P2093
Bruce Magun
Christopher Corless
Mihail Iordanov
Veselina Korcheva
P2860
P304
P356
10.1016/S0002-9440(10)62256-0
P407
P50
P577
2005-01-01T00:00:00Z