CTLA-4 activation of phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B (PKB/AKT) sustains T-cell anergy without cell death.
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Signaling in T cells - is anything the m(a)TOR with the picture(s)?CD28 and CTLA-4 coreceptor expression and signal transductionModulation of cell signaling networks after CTLA4 blockade in patients with metastatic melanomaSuppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects.Immature and maturation-resistant human dendritic cells generated from bone marrow require two stimulations to induce T cell anergy in vitro.Association between the Cytotoxic T-lymphocyte antigen 4 +49G > A polymorphism and cancer risk: a meta-analysis.CTLA4 blockade induces frequent tumor infiltration by activated lymphocytes regardless of clinical responses in humans.Association between CTLA-4 rs231775 polymorphism and risk of colorectal cancer: a meta analysisBiomarkers on melanoma patient T cells associated with ipilimumab treatment.Patients with chronic lymphocytic leukaemia (CLL) differ in the pattern of CTLA-4 expression on CLL cells: the possible implications for immunotherapy with CTLA-4 blocking antibodyAt the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapyCTLA-4 affects expression of key cell cycle regulators of G0/G1 phase in neoplastic lymphocytes from patients with chronic lymphocytic leukaemia.CD28 co-signaling in the adaptive immune response.Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 familyManagement of cutaneous T cell lymphoma: new and emerging targets and treatment options.Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells.The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function.Confusing signals: recent progress in CTLA-4 biologyCTLA-4 co-receptor impacts on the function of Treg and CD8+ T-cell subsetsIntratumoral checkpoint subversion as a strategy for minimizing adverse effects: Harvesting the power of TILs without harvesting TILs.The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses.Tregs: Where We Are and What Comes Next?Glycogen Synthase Kinase 3 Inactivation Compensates for the Lack of CD28 in the Priming of CD8+ Cytotoxic T-Cells: Implications for anti-PD-1 Immunotherapy."Immune TOR-opathies," a Novel Disease Entity in Clinical Immunology.
P2860
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P2860
CTLA-4 activation of phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B (PKB/AKT) sustains T-cell anergy without cell death.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
CTLA-4 activation of phosphati ...... ell anergy without cell death.
@ast
CTLA-4 activation of phosphati ...... ell anergy without cell death.
@en
type
label
CTLA-4 activation of phosphati ...... ell anergy without cell death.
@ast
CTLA-4 activation of phosphati ...... ell anergy without cell death.
@en
prefLabel
CTLA-4 activation of phosphati ...... ell anergy without cell death.
@ast
CTLA-4 activation of phosphati ...... ell anergy without cell death.
@en
P2093
P2860
P1433
P1476
CTLA-4 activation of phosphati ...... ell anergy without cell death.
@en
P2093
Christopher E Rudd
Helga Schneider
Rufina Leung
P2860
P356
10.1371/JOURNAL.PONE.0003842
P407
P577
2008-12-04T00:00:00Z