The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy.
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Infliximab-Related Infusion Reactions: Systematic ReviewDistinct transcriptome profiles differentiate nonsteroidal anti-inflammatory drug-dependent from nonsteroidal anti-inflammatory drug-independent food-induced anaphylaxis.Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal StudiesGenomic responses during acute human anaphylaxis are characterized by upregulation of innate inflammatory gene networks.An in vitro model of antibody-enhanced killing of the intracellular parasite Leishmania amazonensisFc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds.Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor.Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases.RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever.The Early Expression of HLA-DR and CD64 Myeloid Markers Is Specifically Compartmentalized in the Blood and Lungs of Patients with Septic Shock.IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escapeFood allergy: Insights into etiology, prevention, and treatment provided by murine models.The immunology of food allergy.Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions.The function of Fcγ receptors in dendritic cells and macrophages.Mouse and human FcR effector functions.bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.The many faces of FcγRI: implications for therapeutic antibody function.The high-affinity receptor for IgG, FcγRI, of humans and non-human primates.Structural analysis of Fc/FcγR complexes: a blueprint for antibody design.Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model.Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy.Regulation of antibody effector functions through IgG Fc N-glycosylation.Deglycosylation of mAb by EndoS for improved molecular imaging.Up-regulation of CD64-expressing monocytes with impaired FcγR function reflects disease activity in polyarticular psoriatic arthritis.Alternative Anaphylactic Routes: The Potential Role of MacrophagesLeukocyte immunoglobulin-like receptor B4 regulates key signalling molecules involved in FcγRI-mediated clathrin-dependent endocytosis and phagocytosis.Mechanisms, Cofactors, and Augmenting Factors Involved in Anaphylaxis.Therapeutic antibodies and infectious diseases, Tours, France, November 20-22, 2012.IgG subclasses determine pathways of anaphylaxis in mice.Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.Vectors for Expression of Signal Peptide-Dependent Proteins in Baculovirus/Insect Cell Systems and Their Application to Expression and Purification of the High-Affinity Immunoglobulin Gamma Fc Receptor I in Complex with Its Gamma Chain.The pathophysiology of anaphylaxis.Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells.Primitive macrophages control HSPC mobilization and definitive haematopoiesis.Novel drug and soluble target tolerant antidrug antibody assay for therapeutic antibodies bearing the P329G mutation.Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcγRI and IgE domains.Detection of antidrug antibodies against human therapeutic antibodies lacking Fc-effector functions by usage of soluble Fcγ receptor I.CD64: An Attractive Immunotherapeutic Target for M1-type Macrophage Mediated Chronic Inflammatory Diseases.
P2860
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P2860
The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The high-affinity human IgG re ...... , and antitumor immunotherapy.
@ast
The high-affinity human IgG re ...... , and antitumor immunotherapy.
@en
type
label
The high-affinity human IgG re ...... , and antitumor immunotherapy.
@ast
The high-affinity human IgG re ...... , and antitumor immunotherapy.
@en
prefLabel
The high-affinity human IgG re ...... , and antitumor immunotherapy.
@ast
The high-affinity human IgG re ...... , and antitumor immunotherapy.
@en
P2093
P1433
P1476
The high-affinity human IgG re ...... , and antitumor immunotherapy.
@en
P2093
Bruno Iannascoli
David A Mancardi
Friederike Jönsson
Marc Daëron
Nico Van Rooijen
Patrick England
Xiaoqiang Kang
P304
P356
10.1182/BLOOD-2012-07-442541
P407
P577
2013-01-04T00:00:00Z