Transcriptional infidelity promotes heritable phenotypic change in a bistable gene network.
about
GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotidesLost in transcription: transient errors in information transferTranscriptional mutagenesis and its potential roles in the etiology of cancer and bacterial antibiotic resistanceHeritable change caused by transient transcription errorsA canonical model of multistability and scale-invariance in biological systemsPre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switchEmergent bistability by a growth-modulating positive feedback circuitHigh-throughput tracking of single yeast cells in a microfluidic imaging matrix.Misincorporation by RNA polymerase is a major source of transcription pausing in vivoFrail hypotheses in evolutionary biology.Unraveling the regulatory connections between two controllers of breast cancer cell fateVisualizing high error levels during gene expression in living bacterial cells.Medicine. Combating evolution to fight disease.A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.Lysogen stability is determined by the frequency of activity bursts from the fate-determining geneEffects of Tet-mediated oxidation products of 5-methylcytosine on DNA transcription in vitro and in mammalian cells.Removal of 8-oxo-GTP by MutT hydrolase is not a major contributor to transcriptional fidelity.Epigenomic plasticity within populations: its evolutionary significance and potential.Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II.Courting disaster: How diversification rate affects fitness under risk.Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA.Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise.Revisiting bistability in the lysis/lysogeny circuit of bacteriophage lambda.RNA editing by T7 RNA polymerase bypasses InDel mutations causing unexpected phenotypic changes.Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo.Rifampin Resistance rpoB Alleles or Multicopy Thioredoxin/Thioredoxin Reductase Suppresses the Lethality of Disruption of the Global Stress Regulator spx in Staphylococcus aureusDksA involvement in transcription fidelity buffers stochastic epigenetic change.Isolation and characterization of RNA polymerase rpoB mutations that alter transcription slippage during elongation in Escherichia coliUBE2B mRNA alterations are associated with severe oligozoospermia in infertile men.The effect of LacI autoregulation on the performance of the lactose utilization system in Escherichia coli.Direct assessment of transcription fidelity by high-resolution RNA sequencing.Decision making in living cells: lessons from a simple system.Programmed heterogeneity: epigenetic mechanisms in bacteria.What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.Phenotypic Diversity as a Mechanism to Exit Cellular Dormancy.Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations.Genome-Wide Spectra of Transcription Insertions and Deletions Reveal That Slippage Depends on RNA:DNA Hybrid Complementarity.A link between transcription fidelity and pausing in vivo.Characterization of a novel RNA polymerase mutant that alters DksA activity.
P2860
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P2860
Transcriptional infidelity promotes heritable phenotypic change in a bistable gene network.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Transcriptional infidelity pro ...... ge in a bistable gene network.
@ast
Transcriptional infidelity pro ...... ge in a bistable gene network.
@en
type
label
Transcriptional infidelity pro ...... ge in a bistable gene network.
@ast
Transcriptional infidelity pro ...... ge in a bistable gene network.
@en
prefLabel
Transcriptional infidelity pro ...... ge in a bistable gene network.
@ast
Transcriptional infidelity pro ...... ge in a bistable gene network.
@en
P2093
P2860
P1433
P1476
Transcriptional infidelity pro ...... ge in a bistable gene network.
@en
P2093
Alasdair J E Gordon
Christophe Herman
Fumio Yatagai
Jennifer A Halliday
Matthew D Blankschien
Philip A Burns
P2860
P356
10.1371/JOURNAL.PBIO.1000044
P407
P577
2009-02-01T00:00:00Z