The dual role model for p53 in maintaining genomic integrity.
about
Stress-dependent nucleolin mobilization mediated by p53-nucleolin complex formationProapoptotic p53-interacting protein 53BP2 is induced by UV irradiation but suppressed by p53Knockout and transgenic mice of Trp53: what have we learned about p53 in breast cancer?Genetic Stabilization by p53 Involves Growth Regulatory and Repair PathwaysIntegrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosisRecombinant p53 displays heterogeneity during isoelectric focusing.Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase.The role of the E6-p53 interaction in the molecular pathogenesis of HPV.Defect in the p53-Mdm2 autoregulatory loop resulting from inactivation of TAF(II)250 in cell cycle mutant tsBN462 cells.p53 Ser15 phosphorylation disrupts the p53-RPA70 complex and induces RPA70-mediated DNA repair in hypoxia.The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis.Adenoviral-E2F-1 radiosensitizes p53wild-type and p53null human prostate cancer cells.Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic responseEmerging models and paradigms for stem cell ageing.Evidence for activation of mutated p53 by apigenin in human pancreatic cancer.Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils.Oncogene and tumor-suppressor gene products as serum biomarkers in occupational-derived lung cancer.Versatile functions of p53 protein in multicellular organismsSmall interfering RNA-directed knockdown of uracil DNA glycosylase induces apoptosis and sensitizes human prostate cancer cells to genotoxic stress.Novel HIV-1 therapeutics through targeting altered host cell pathways.Unravelling mechanisms of cisplatin sensitivity and resistance in testicular cancer.Different recognition of DNA modified by aatitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53.Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53.DNA Structure and Polymerase Fidelity: A New Role for A-DNA.Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.Different regulation of the p53 core domain activities 3'-to-5' exonuclease and sequence-specific DNA bindingDown-regulation of beta-catenin by activated p53.Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formationEpstein-Barr virus latent membrane protein 1 represses p53-mediated DNA repair and transcriptional activity.Iron deprivation induces apoptosis independently of p53 in human and murine tumour cells.Structural and functional involvement of p53 in BER in vitro and in vivo.Substrate specificity of the p53-associated 3'-5' exonuclease.Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control.Intraperitoneal dedifferentiated liposarcoma: a case report.Elevated transcription of the p53 gene in early S-phase leads to a rapid DNA-damage response during S-phase of the cell cycle.Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery.Binding of p53 and its core domain to supercoiled DNA.The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA.
P2860
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P2860
The dual role model for p53 in maintaining genomic integrity.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The dual role model for p53 in maintaining genomic integrity.
@ast
The dual role model for p53 in maintaining genomic integrity.
@en
The dual role model for p53 in maintaining genomic integrity.
@nl
type
label
The dual role model for p53 in maintaining genomic integrity.
@ast
The dual role model for p53 in maintaining genomic integrity.
@en
The dual role model for p53 in maintaining genomic integrity.
@nl
prefLabel
The dual role model for p53 in maintaining genomic integrity.
@ast
The dual role model for p53 in maintaining genomic integrity.
@en
The dual role model for p53 in maintaining genomic integrity.
@nl
P2093
P356
P1476
The dual role model for p53 in maintaining genomic integrity.
@en
P2093
Albrechtsen N
Dornreiter I
Wiesmüller L
P2888
P356
10.1007/S000180050266
P577
1999-01-01T00:00:00Z