Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.
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Towards Antitumor Active trans-Platinum Compounds.A potent cytotoxic photoactivated platinum complexPromotion of DNA strand breaks, interstrand cross-links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexesDiazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.Biophysical studies on the stability of DNA intrastrand cross-links of transplatin.Compensation of DNA stabilization and destabilization effects caused by cisplatin is partially disturbed in alkaline medium.DNA modification with cisplatin affects sequence-specific DNA binding of p53 and p73 proteins in a target site-dependent manner.
P2860
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P2860
Recognition of DNA modified by trans-[PtClNH(4-hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic complex.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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name
Recognition of DNA modified by ...... cts of this cytotoxic complex.
@en
type
label
Recognition of DNA modified by ...... cts of this cytotoxic complex.
@en
prefLabel
Recognition of DNA modified by ...... cts of this cytotoxic complex.
@en
P2093
P2860
P1433
P1476
Recognition of DNA modified by ...... ucts of this cytotoxic complex
@en
P2093
Alberto Martínez
Jana Kaspárková
Kristýna Stehlíková
Olga Nováková
Virtudes Moreno
P2860
P304
P356
10.1111/J.1742-4658.2005.05061.X
P407
P577
2006-01-01T00:00:00Z