Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.
about
Insulin in the brain: there and back againNeuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrierRoles of low-density lipoprotein receptor-related protein 1 in tumorsLDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like regionIdentifying Driver Genomic Alterations in Cancers by Searching Minimum-Weight, Mutually Exclusive SetsHeparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.Neuronal clearance of amyloid-β by endocytic receptor LRP1.Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal traffickingLRP-1 promotes cancer cell invasion by supporting ERK and inhibiting JNK signaling pathwaysTackling obstacles for gene therapy targeting neurons: disrupting perineural nets with hyaluronidase improves transduction.Hepatic deficiency of low density lipoprotein receptor-related protein-1 reduces high density lipoprotein secretion and plasma levels in miceSorting nexin 17 regulates ApoER2 recycling and reelin signalingThe unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury.α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death.Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke riskThe NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration.LRP1 Downregulates the Alzheimer's β-Secretase BACE1 by Modulating Its Intraneuronal Trafficking(1,2,3).Mesenchymal Stromal Cells Promote Axonal Outgrowth Alone and Synergistically with Astrocytes via tPAProtumorigenic activity of plasminogen activator inhibitor-1 through an antiapoptotic functionBreast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic EnvironmentA sorting nexin 17-binding domain within the LRP1 cytoplasmic tail mediates receptor recycling through the basolateral sorting endosome.Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration.Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons.LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury.Dissecting the association between migraine and stroke.Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.Exploration of effects of emodin in selected cancer cell lines: enhanced growth inhibition by ascorbic acid and regulation of LRP1 and AR under hypoxia-like conditions.Coexpression Analysis of Transcriptome on AIDS and Other Human Disease Pathways by Canonical Correlation Analysis.Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan.Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains.LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease.Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells.MicroRNA-146a represses LRP2 translation and leads to cell apoptosis in Alzheimer's disease.Blockade of extracellular heat shock protein 90α by 1G6-D7 attenuates pulmonary fibrosis through inhibiting ERK signaling.LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair.Amyloid-beta levels are significantly reduced and spatial memory defects are rescued in a novel neuroserpin-deficient Alzheimer's disease transgenic mouse model.Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.
P2860
Q26825385-8FF27F1E-9EE2-4C1C-A285-17EAA2383C53Q27022365-7AA4E3BA-D38C-469A-A4D5-40329E2DCFFEQ28078531-83A7EF1D-97E0-4845-8E44-BE2484D46284Q28571064-7DE67F11-0403-43C1-A12E-C948CF80E512Q28592005-C8DC7CC0-B34A-4AF7-AC9F-7A673BE75E60Q28608346-751600CF-6E66-4318-8F3A-A716062637E1Q29976923-58ADA70E-6322-41B9-9AB1-5EF3A5A8B34EQ29977780-6ACAC495-4A41-4D44-8065-61FF6BDE8311Q33649821-BD5EE1CE-5DA0-4FF8-A8EB-8B4019AF8381Q33996198-8D4CDCE4-4194-4519-BE90-D2196E49A94BQ34542412-A35D7EEB-98B9-4E6C-9E17-029FC18D7EA2Q34787076-E0954038-C93E-47D0-BFEF-F20A23F6233CQ35140164-9B222904-2832-421F-868D-6C49C69D9FA9Q35283038-50FB3512-4641-4FBD-B0A4-8D12AF392C12Q35763065-3AE05C29-EE8A-405E-99A6-4DE6E3A22619Q35832752-7E506CED-0A03-4FD5-B2D0-BF8BD8A9C71CQ36125572-D780B5CD-8025-439D-B836-3513B8901142Q36130037-016AF3FA-FCFB-4AEB-9AD7-091428DFC56AQ36222296-E66FE281-CE2C-47D6-8069-C2A2C6CB24E3Q36486880-146D3602-D827-41A9-A2A1-7F497C239884Q36548865-FB7B6FDD-7FFA-411B-9B76-534893629108Q36920248-26ABFE86-435B-4424-8BB5-F640B474DEA4Q37168384-B1C0111B-7F18-4285-8D82-9346DEDE98E3Q37192393-CBA3B3F6-D557-4B72-BB57-657A05D6C646Q37333802-B1CDCB12-9460-48EF-950A-B71D76BBD3A1Q38145431-E02B3D94-2104-4FFA-9EB1-42FDE2CEA4CBQ38344344-02E667BA-FC94-4404-B421-61D9923341B9Q39222720-ECA7498E-F042-42E5-9990-7AE0825F8AD0Q39232171-63244D16-CADF-40D4-8FA8-AD3087F51008Q40128097-EB387B5E-B461-4550-9DF3-AF84A16817CAQ41023255-DFB9247C-5F1D-41F1-9D0F-B4E46689AF42Q41161172-EBDBD28F-279B-44B8-97F0-98162CC4F222Q41653633-359E426A-02CA-4BB2-8FA6-4B2E5F55B8E8Q42321517-C9883FE0-F965-47DC-81A0-16D314967693Q42459554-A0CA0A1A-75B7-4AFC-922A-1B1C826902C1Q43753603-E143D602-4A99-40DE-A092-F6B5984A2460Q46592340-F117A0B7-7DEB-48EF-BECA-6BECE28E423EQ47130977-A4F58DC1-6D1B-461B-A047-3B9B8B459A80Q49150181-A88E0399-2EA9-41E3-8709-D037A3DD59F2Q49851052-325AA7BA-FD63-48AE-89B9-8E2CC29A750A
P2860
Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Low density lipoprotein recept ...... tivating Akt survival pathway.
@ast
Low density lipoprotein recept ...... tivating Akt survival pathway.
@en
Low density lipoprotein recept ...... tivating Akt survival pathway.
@nl
type
label
Low density lipoprotein recept ...... tivating Akt survival pathway.
@ast
Low density lipoprotein recept ...... tivating Akt survival pathway.
@en
Low density lipoprotein recept ...... tivating Akt survival pathway.
@nl
prefLabel
Low density lipoprotein recept ...... tivating Akt survival pathway.
@ast
Low density lipoprotein recept ...... tivating Akt survival pathway.
@en
Low density lipoprotein recept ...... tivating Akt survival pathway.
@nl
P2093
P2860
P356
P1476
Low density lipoprotein recept ...... tivating Akt survival pathway.
@en
P2093
Juan Zhang
Takahisa Kanekiyo
P2860
P304
34045-34053
P356
10.1074/JBC.M109.021030
P407
P577
2009-10-08T00:00:00Z