Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1
about
Interactions of metals and Apolipoprotein E in Alzheimer's diseaseTransthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?CD74 interacts with APP and suppresses the production of AbetaBRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyApolipoprotein E receptors in the nervous systemLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseSoluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APPAmyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta poresNeuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathwaysThe low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's diseasePlatelet biomarkers in Alzheimer's diseaseApolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer diseaseInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseCholesterol balance in prion diseases and Alzheimer's diseaseAmyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's diseaseOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseAPP processing in Alzheimer's diseaseProteolytic processing of Alzheimer's β-amyloid precursor proteinThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseTransgenic expression of the amyloid-beta precursor protein-intracellular domain does not induce Alzheimer's Disease-like traits in vivoLRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein traffickingThe multi-copy mouse gene Sycp3-like Y-linked (Sly) encodes an abundant spermatid protein that interacts with a histone acetyltransferase and an acrosomal proteinMultiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP)Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaksAmyloid precursor protein trafficking, processing, and functionLRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.Neuronal clearance of amyloid-β by endocytic receptor LRP1.Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearanceLymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified γ-secretase complexes.Gene expression profiling in cells with enhanced gamma-secretase activity.Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.Cross-talk of membrane lipids and Alzheimer-related proteins.Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal traffickingRetinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo.Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking
P2860
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P248
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P2860
Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@ast
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@en
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@nl
type
label
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@ast
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@en
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@nl
prefLabel
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@ast
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@en
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@nl
P2093
P2860
P921
P3181
P1433
P1476
Amyloid precursor protein regu ...... ough lipoprotein receptor LRP1
@en
P2093
Baiping Wang
Celina V Zerbinatti
Hyang-Sook Hoe
Joachim Herz
Juan Zhang
Louis Muglia
Sarah L Cole
P2860
P3181
P356
10.1016/J.NEURON.2007.08.008
P407
P577
2007-10-04T00:00:00Z