Discovery of novel benzoxaborole-based potent antitrypanosomal agents. - Test2 - elhamkhani - TriplyDB

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

http://www.wikidata.org/entity/Q33557952

about

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis tRNAs as antibiotic targets Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors.Whole-organism high-throughput screening against Trypanosoma brucei brucei.Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing.Synthesis and evaluation of functionalized benzoboroxoles as potential anti-tuberculosis agents.A Divalent Protecting Group for Benzoxaboroles.Development of novel drugs for human African trypanosomiasis.Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.Discovery of N-(4-sulfamoylphenyl)thioureas as Trypanosoma brucei leucyl-tRNA synthetase inhibitors.Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.In Vitro and In Vivo Activity of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens.One-pot synthesis of benzoxaborole derivatives from the palladium-catalyzed cross-coupling reaction of alkoxydiboron with unprotected o-bromobenzylalcohols.Synthesis, Reactivity, Functionalization, and ADMET Properties of Silicon-Containing Nitrogen Heterocycles.Current and Future Strategies for Improving Drug Discovery Efficiency The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

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Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

http://www.wikidata.org/entity/Q33557952

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@ast

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@en

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@nl

type

label

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@ast

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@en

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@nl

prefLabel

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@ast

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@en

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@nl

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ACS Medicinal Chemistry Letters

P1476

Discovery of novel benzoxaborole-based potent antitrypanosomal agents.

@en

P2093

Bakela Nare

http://www.w3.org/2001/XMLSchema#string

Cyrus J Bacchi

http://www.w3.org/2001/XMLSchema#string

Daitao Chen

http://www.w3.org/2001/XMLSchema#string

Dazhong Ding

http://www.w3.org/2001/XMLSchema#string

Dongsheng Xie

http://www.w3.org/2001/XMLSchema#string

Huchen Zhou

http://www.w3.org/2001/XMLSchema#string

Jacob J Plattner

http://www.w3.org/2001/XMLSchema#string

Joseline Ratnam

http://www.w3.org/2001/XMLSchema#string

Kean-Hooi Ang

http://www.w3.org/2001/XMLSchema#string

Maha Abdulla

http://www.w3.org/2001/XMLSchema#string

P2860

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

Control of neglected tropical diseases

Opportunities and Challenges in Antiparasitic Drug Discovery

Treatment of human African trypanosomiasis--present situation and needs for research and development.

Chemotherapy of trypanosomiases and leishmaniasis.

Drug discovery and development for neglected parasitic diseases.

Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis.

Copper/amino acid catalyzed cross-couplings of aryl and vinyl halides with nucleophiles.

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165-169

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scholarly article

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10.1021/ML100013S

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4

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1

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James H McKerrow

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2010-04-06T00:00:00Z

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231711948

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24900190

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4007846

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