Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
about
Emerging roles of the nucleolus in regulating the DNA damage response: the noncanonical DNA repair enzyme APE1/Ref-1 as a paradigmatical exampleGenetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activityNucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cellsUbiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5.Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.BRCA1 modulates the expression of hnRNPA2B1 and KHSRP.Regulatory mechanisms of RNA function: emerging roles of DNA repair enzymes.APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsRedox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitisHighly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway.Transfected early growth response gene-1 DNA enzyme prevents stenosis and occlusion of autogenous vein graft in vivoIdentification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry.Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells.The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate.Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and functionMonoclonal antibodies against pools of mono- and polyacetylated peptides selectively recognize acetylated lysines within the context of the original antigenRNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression.Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions.SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements.Recognition of damaged DNA: structure and dynamic markers.A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions.Dual roles of DNA repair enzymes in RNA biology/post-transcriptional control.Crosstalk between the nucleolus and the DNA damage response.Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit.Crystallization and preliminary X-ray analysis of human endonuclease 1 (APE1) in complex with an oligonucleotide containing a 5,6-dihydrouracil (DHU) or an alpha-anomeric 2'-deoxyadenosine (alphadA) modified base.Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2.Molecular snapshots of APE1 proofreading mismatches and removing DNA damage.Placental aging and oxidation damage in a tissue micro-array model: an immunohistochemistry study.Prognostic significance of APE1 cytoplasmic localization in human epithelial ovarian cancer.
P2860
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P2860
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
description
2009 nî lūn-bûn
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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@ast
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@en
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@nl
type
label
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@ast
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@en
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@nl
prefLabel
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@ast
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@en
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@nl
P2860
P356
P1476
Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?
@en
P2093
Chow H Lee
David M Wilson
P2860
P304
P356
10.1128/MCB.01174-09
P407
P577
2009-11-09T00:00:00Z