Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence.
about
Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relationsMassively parallel measurements of molecular interaction kinetics on a microfluidic platform.Synthetic biology outside the cell: linking computational tools to cell-free systemsVersatility of cooperative transcriptional activation: a thermodynamical modeling analysis for greater-than-additive and less-than-additive effectsTowards structural systems pharmacology to study complex diseases and personalized medicineDefining the DNA uptake specificity of naturally competent Haemophilus influenzae cells.The transcription factor titration effect dictates level of gene expression.Parametric inference in the large data limit using maximally informative models.A genome-integrated massively parallel reporter assay reveals DNA sequence determinants of cis-regulatory activity in neural cellsStatistical mechanical model of coupled transcription from multiple promoters due to transcription factor titration.Inferring fitness landscapes by regression produces biased estimates of epistasis.Comparison of the theoretical and real-world evolutionary potential of a genetic circuit.Self-consistent theory of transcriptional control in complex regulatory architectures.Saturation editing of genomic regions by multiplex homology-directed repairSystematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay.Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters.Equitability, mutual information, and the maximal information coefficient.Large-scale mapping of sequence-function relations in small regulatory RNAs reveals plasticity and modularity.Tuning promoter strength through RNA polymerase binding site design in Escherichia coli.Genotype to phenotype mapping and the fitness landscape of the E. coli lac promoter.Massively parallel determination and modeling of endonuclease substrate specificityThe impact of macroscopic epistasis on long-term evolutionary dynamicsComposability of regulatory sequences controlling transcription and translation in Escherichia coliEvolutionary meandering of intermolecular interactions along the drift barrier.D-Tailor: automated analysis and design of DNA sequencesComparing binding site information to binding affinity reveals that Crp/DNA complexes have several distinct binding conformersMassively parallel reporter assays in cultured mammalian cells.Searching for simplicity in the analysis of neurons and behaviorQuality versus accuracy: result of a reanalysis of protein-binding microarrays from the DREAM5 challenge by using BayesPI2 including dinucleotide interdependence.Quantitative analysis of mammalian translation initiation sites by FACS-seqRelationship between promoter sequence and its strength in gene expression.SORTCERY-A High-Throughput Method to Affinity Rank Peptide Ligands.The influence of promoter architectures and regulatory motifs on gene expression in Escherichia coli.Protein evolution. Pervasive degeneracy and epistasis in a protein-protein interface.Systematic dissection of the sequence determinants of gene 3' end mediated expression control.Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences.High-throughput cellular RNA device engineering.Dynamics of Transcription Factor Binding Site Evolution.Combinatorial optimization of CO2 transport and fixation to improve succinate production by promoter engineering.Generating High-Accuracy Peptide-Binding Data in High Throughput with Yeast Surface Display and SORTCERY.
P2860
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P2860
Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Using deep sequencing to chara ...... riptional regulatory sequence.
@ast
Using deep sequencing to chara ...... riptional regulatory sequence.
@en
Using deep sequencing to chara ...... riptional regulatory sequence.
@nl
type
label
Using deep sequencing to chara ...... riptional regulatory sequence.
@ast
Using deep sequencing to chara ...... riptional regulatory sequence.
@en
Using deep sequencing to chara ...... riptional regulatory sequence.
@nl
prefLabel
Using deep sequencing to chara ...... riptional regulatory sequence.
@ast
Using deep sequencing to chara ...... riptional regulatory sequence.
@en
Using deep sequencing to chara ...... riptional regulatory sequence.
@nl
P2093
P2860
P356
P1476
Using deep sequencing to chara ...... riptional regulatory sequence.
@en
P2093
Anand Murugan
Curtis G Callan
Edward C Cox
P2860
P304
P356
10.1073/PNAS.1004290107
P407
P577
2010-05-03T00:00:00Z