Mutation of aspartic acid-351, lysine-352, and lysine-515 alters the Ca2+ transport activity of the Ca2+-ATPase expressed in COS-1 cells.
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Purified E255L Mutant SERCA1a and Purified PfATP6 Are Sensitive to SERCA-type Inhibitors but Insensitive to ArtemisininsSERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.Mitochondrial BCL-2 inhibits AMBRA1-induced autophagyFunctional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analysesFunctional difference between SERCA2a and SERCA2b Ca2+ pumps and their modulation by phospholambanSarcolipin uncouples hydrolysis of ATP from accumulation of Ca2+ by the Ca2+-ATPase of skeletal-muscle sarcoplasmic reticulumMolecular cloning and expression of cDNA encoding a lumenal calcium binding glycoprotein from sarcoplasmic reticulumMutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS.SERCA mutant E309Q binds two Ca2+ions but adopts a catalytically incompetent conformationPMR1, a Ca2+-ATPase in yeast Golgi, has properties distinct from sarco/endoplasmic reticulum and plasma membrane calcium pumps.Mechanistic studies of phosphoserine phosphatase, an enzyme related to P-type ATPasesTransmembrane helix M6 in sarco(endo)plasmic reticulum Ca(2+)-ATPase forms a functional interaction site with phospholamban. Evidence for physical interactions at other sitesMutations of either or both Cys876 and Cys888 residues of sarcoplasmic reticulum Ca2+-ATPase result in a complete loss of Ca2+ transport activity without a loss of Ca2+-dependent ATPase activity. Role of the CYS876-CYS888 disulfide bondThe effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitorsMolecular Cloning and Characterization of a Novel Form of Neuropeptide Gene as a Developmentally Regulated MoleculeSarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals.Low temperature molecular adaptation of the skeletal muscle sarco(endo)plasmic reticulum Ca2+-ATPase 1 (SERCA 1) in the wood frog (Rana sylvatica).Precise amounts of a novel member of a phosphotransferase superfamily are essential for growth and normal morphology in Caulobacter crescentus.Glutamate 90 at the luminal ion gate of sarcoplasmic reticulum Ca2+-ATPase is critical for Ca(2+) binding on both sides of the membrane.High-yield heterologous expression of wild type and mutant Ca(2+) ATPase: Characterization of Ca(2+) binding sites by charge transfer.Simulation of coherent energy transfer in an alpha-helical peptide by Fermi resonance.Mutagenesis of the yeast plasma membrane H(+)-ATPase. A novel expression system.Superinhibitory phospholamban mutants compete with Ca2+ for binding to SERCA2a by stabilizing a unique nucleotide-dependent conformational state.Three-dimensional crystals of CaATPase from sarcoplasmic reticulum. Symmetry and molecular packing.Molecular tools to elucidate problems in excitation-contraction couplingTopology of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum (RyR1).Recent progress in histochemistry and cell biology.Roles of conserved P domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase.Critical roles of interdomain interactions for modulatory ATP binding to sarcoplasmic reticulum Ca2+-ATPaseMutational analysis of the conserved TGES loop of sarcoplasmic reticulum Ca2+-ATPase.Modulatory ATP binding affinity in intermediate states of E2P dephosphorylation of sarcoplasmic reticulum Ca2+-ATPase.Structure and function of the yeast plasma-membrane H(+)-ATPase.Structure-function relationships in sarcoplasmic or endoplasmic reticulum type Ca2+ pumps.Characterization and expression of the rat heart sarcoplasmic reticulum Ca2+-ATPase mRNA.The Effect of SERCA1b Silencing on the Differentiation and Calcium Homeostasis of C2C12 Skeletal Muscle CellsDominant lethal mutations in the plasma membrane H(+)-ATPase gene of Saccharomyces cerevisiaeIdentification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle.Distinct roles of the C-terminal 11th transmembrane helix and luminal extension in the partial reactions determining the high Ca2+ affinity of sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2b (SERCA2b).Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy.Sarcolipin protein interaction with sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is distinct from phospholamban protein, and only sarcolipin can promote uncoupling of the SERCA pump.
P2860
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P2860
Mutation of aspartic acid-351, lysine-352, and lysine-515 alters the Ca2+ transport activity of the Ca2+-ATPase expressed in COS-1 cells.
description
1988 nî lūn-bûn
@nan
1988 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@ast
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@en
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@nl
type
label
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@ast
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@en
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@nl
prefLabel
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@ast
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@en
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@nl
P2860
P356
P1476
Mutation of aspartic acid-351, ...... Pase expressed in COS-1 cells.
@en
P2093
MacLennan DH
Maruyama K
P2860
P304
P356
10.1073/PNAS.85.10.3314
P407
P577
1988-05-01T00:00:00Z