Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
about
Progress toward in vivo use of siRNAs-IIEffects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs.The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation siteMinimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in MicePreclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing.Northern blotting analysis of microRNAs, their precursors and RNA interference triggers.Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100.GTAG- and CGTC-tagged palindromic DNA repeats in prokaryotesFormulated minimal-length synthetic small hairpin RNAs are potent inhibitors of hepatitis C virus in mice with humanized livers.Towards Antiviral shRNAs Based on the AgoshRNA Design.Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering.Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effectsRight- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencingA new design of a lentiviral shRNA vector with inducible co-expression of ARGONAUTE 2 for enhancing gene silencing efficiency.Embedding siRNA sequences targeting apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacyInhibition of hepatitis C virus in chimeric mice by short synthetic hairpin RNAs: sequence analysis of surviving virus shows added selective pressure of combination therapy.Lentiviral vector-mediated RNA silencing in the central nervous system.Towards improved shRNA and miRNA reagents as inhibitors of HIV-1 replication.Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2.Toward optimization of AgoshRNA molecules that use a non-canonical RNAi pathway: variations in the top and bottom base pairs.An intracellular buildup reaction of active siRNA species from short RNA fragments.Dicer-independent processing of short hairpin RNAs.Synthetic Pre-miRNA-Based shRNA as Potent RNAi Triggers.Influence of the loop size and nucleotide composition on AgoshRNA biogenesis and activity.Silencing of HIV-1 by AgoshRNA molecules.Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming.Dicer-independent processing of small RNA duplexes: mechanistic insights and applications.Molecular Properties, Functional Mechanisms, and Applications of Sliced siRNA.Designing Ago2-specific siRNA/shRNA to Avoid Competition with Endogenous miRNAs.Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity.Induction of RNAi Responses by Short Left-Handed Hairpin RNAi Triggers.RNAi-induced off-target effects in Drosophila melanogaster: frequencies and solutions.Differences in silencing of mismatched targets by sliced versus diced siRNAs.
P2860
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P2860
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
@ast
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
@en
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity.
@nl
type
label
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
@ast
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
@en
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity.
@nl
prefLabel
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
@ast
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
@en
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity.
@nl
P2093
P2860
P356
P1433
P1476
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity
@en
P2093
Anne Dallas
Heini Ilves
Joshua Shorenstein
Pavan Kumar
Sergei A Kazakov
P2860
P304
P356
10.1261/RNA.1894510
P407
P577
2009-12-01T00:00:00Z