siRNA-mediated off-target gene silencing triggered by a 7 nt complementation - Test2 - elhamkhani - TriplyDB

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

http://www.wikidata.org/entity/Q24812419

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p53 activation by knockdown technologies Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?Is the Efficiency of RNA Silencing Evolutionarily Regulated?siRNA Versus miRNA as Therapeutics for Gene Silencing Fighting against kidney diseases with small interfering RNA: opportunities and challenges Abasic pivot substitution harnesses target specificity of RNA interference siRNA off-target effects can be reduced at concentrations that match their individual potency Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2 siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect.Enzymatically prepared RNAi libraries.'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.Chemogenomics approaches to novel target discovery.A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation Designer siRNAs to overcome the challenges from the RNAi pathway.Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity Design and evaluation of genome-wide libraries for RNA interference screens High throughput genome-wide survey of small RNAs from the parasitic protists Giardia intestinalis and Trichomonas vaginalis Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration An off-target nucleostemin RNAi inhibits growth in human glioblastoma-derived cancer stem cells High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit them E-cadherin is transcriptionally activated via suppression of ZEB1 transcriptional repressor by small RNA-mediated gene silencing.A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens siRNA has greatly elevated mismatch tolerance at 3'-UTR sites.Combined small interfering RNA therapy and in vivo magnetic resonance imaging in islet transplantation Insights into cellular factors that regulate HIV-1 replication in human cells A library of TAL effector nucleases spanning the human genome.A role for human Dicer in pre-RISC loading of siRNAs.RNAi therapeutics: principles, prospects and challenges.Off-target effects by siRNA can induce toxic phenotype.RNA interference for improving the outcome of islet transplantation.RNAi induces innate immunity through multiple cellular signaling pathways.RNA interference screening for the discovery of oncology targets.SeedSeq: off-target transcriptome database.Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells Comparison of siRNA-induced off-target RNA and protein effects Carbon nanotubes part II: a remarkable carrier for drug and gene delivery RNAe: an effective method for targeted protein translation enhancement by artificial non-coding RNA with SINEB2 repeat.Multiplexing siRNAs to compress RNAi-based screen size in human cells.Vigilance and validation: Keys to success in RNAi screening.

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

http://www.wikidata.org/entity/Q24812419

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2005 nî lūn-bûn

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2005 թուականին հրատարակուած գիտական յօդուած

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2005 թվականին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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type

label

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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prefLabel

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

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Nucleic Acids Research

P1476

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

@en

P2093

Jeffrey A McDowell

http://www.w3.org/2001/XMLSchema#string

Mark G Anderson

http://www.w3.org/2001/XMLSchema#string

Paul E Kroeger

http://www.w3.org/2001/XMLSchema#string

Xiaoan Ruan

http://www.w3.org/2001/XMLSchema#string

Xiaoyu Lin

http://www.w3.org/2001/XMLSchema#string

Yu Shen

http://www.w3.org/2001/XMLSchema#string

P2860

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

Prediction of mammalian microRNA targets

Targeting HIF-1 for cancer therapy

Asymmetry in the assembly of the RNAi enzyme complex

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Functional siRNAs and miRNAs exhibit strand bias

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Involvement of microRNA in AU-rich element-mediated mRNA instability

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4527-35

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scholarly article

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1679757

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10.1093/NAR/GKI762

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P433

14

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33

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Stephen W. Fesik

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2005-01-01T00:00:00Z

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7668008

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16091630

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1184219

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