BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha. - Test2 - elhamkhani - TriplyDB

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

http://www.wikidata.org/entity/Q33576505

about

STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1 BRCA1 and estrogen/estrogen receptor in breast cancer: where they interact?RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis Epigenetic regulation of persistent pain Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation Minireview: The versatile roles of lysine deacetylases in steroid receptor signaling Effect of BRCA1 on epidermal growth factor receptor in ovarian cancer.Regulation of angiotensin II type 1 receptor expression in ovarian cancer: a potential role for BRCA1 Estrogen signaling and the DNA damage response in hormone dependent breast cancers.MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo.Palmitoylation: a protein S-acylation with implications for breast cancer.Estrogen receptor (ER) α mutations in breast cancer: hidden in plain sight The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation Estrogen receptor mutations and changes in downstream gene expression and signaling Glucocorticoid receptor cofactors as therapeutic targets.Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 New roles of cyclin D1.Small-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-α Acetylation and nuclear receptor action Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells.Glucocorticoid receptor repression mediated by BRCA1 inactivation in ovarian cancer Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models.Ligand-dependent differences in estrogen receptor beta-interacting proteins identified in lung adenocarcinoma cells corresponds to estrogenic responses.Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice.DNA stabilization by the upregulation of estrogen signaling in BRCA gene mutation carriers.Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.A new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance.Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs.Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex.BRCA1/p220 loss triggers BRCA1-IRIS overexpression via mRNA stabilization in breast cancer cells A porcine model system of BRCA1 driven breast cancer.Estrogen signaling and cardiovascular disease.BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9 Derailed estrogen signaling and breast cancer: an authentic couple.Epigenetic regulation of estrogen signaling in breast cancer Estrogen receptor β (ERβ1) transactivation is differentially modulated by the transcriptional coregulator Tip60 in a cis-acting element-dependent manner

P2860

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P2860

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

http://www.wikidata.org/entity/Q33576505

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@ast

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@en

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@nl

type

label

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@ast

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@en

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@nl

prefLabel

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@ast

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@en

BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@nl

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Molecular Endocrinology

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BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.

@en

P2093

Changyan Hu

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Eliot M Rosen

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Qinghui Meng

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Richard G Pestell

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Saijun Fan

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Suzanne A Fuqua

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Yongxian Ma

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York A Tomita

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P2860

Structural determinants of the BRCA1 : estrogen receptor interaction

Growth factor signaling pathways modulate BRCA1 repression of estrogen receptor-alpha activity

BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor

CBP/p300 interact with and function as transcriptional coactivators of BRCA1

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

BRCA1 interacts with components of the histone deacetylase complex

Hypersensitive K303R oestrogen receptor-alpha variant not found in invasive carcinomas

The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

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76-90

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scholarly article

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10.1210/ME.2009-0218

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1

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24

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2009-11-03T00:00:00Z

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19887647

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protein ubiquitination

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2802901

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