Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
about
An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1.Structural and functional characterization of the monomeric U-box domain from E4BStructural determinants of the BRCA1 : estrogen receptor interactionA unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8Highlight: BRCA1 and BRCA2 proteins in breast cancerThe BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitinIdentification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domainsRecognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complexCCDC98 targets BRCA1 to DNA damage sitesStructure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1bStructure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complexProximity-induced activation of human Cdc34 through heterologous dimerization.Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.Control of biochemical reactions through supramolecular RING domain self-assembly.Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chainsHECT and RING finger families of E3 ubiquitin ligases at a glanceSTRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylationBinding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complexEvolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1 gene with missense sequence changes and in-frame deletions, but not polymorphismsA guide for functional analysis of BRCA1 variants of uncertain significanceRING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitinationRINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisThe role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapyThe BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular LocationsA microchip platform for structural oncology applications.The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling.Structural consequences of a cancer-causing BRCA1-BRCT missense mutationStructural insights into the U-box, a domain associated with multi-ubiquitinationStructure, interactions, and dynamics of the RING domain from human TRAF6Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's diseaseStructure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in transCrystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional ConsequencesStructures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitmentImpact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide RecognitionBIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimerMechanism of ubiquitylation by dimeric RING ligase RNF4NMR-based insights into the conformational and interaction properties of Arkadia RING-H2 E3 Ub ligaseSynthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5.The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity.
P2860
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P2860
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@ast
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@en
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@nl
type
label
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@ast
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@en
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@nl
prefLabel
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@ast
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@en
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@nl
P2093
P3181
P356
P1476
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
@en
P2093
P Rajagopal
P S Brzovic
R E Klevit
P304
P3181
P356
10.1038/NSB1001-833
P407
P577
2001-10-01T00:00:00Z