An overview of chemotherapeutic targets for antimalarial drug discovery.
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Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial ParasiteTTD: Therapeutic Target DatabaseCopper pathways in Plasmodium falciparum infected erythrocytes indicate an efflux role for the copper P-ATPaseDisulfide linkages in Plasmodium falciparum plasmepsin-i are essential elements for its processing activity and multi-milligram recombinant production yieldPharmacological properties of a new antimalarial bisthiazolium salt, T3, and a corresponding prodrug, TE3.Lipophilic antifolate trimetrexate is a potent inhibitor of Trypanosoma cruzi: prospect for chemotherapy of Chagas' disease.Antimalarial activities of novel synthetic cysteine protease inhibitors.Eosin B as a novel antimalarial agent for drug-resistant Plasmodium falciparum.Cyclin-dependent protein kinases as therapeutic drug targets for antimalarial drug development.Potent inhibitors of Plasmodium phospholipid metabolism with a broad spectrum of in vitro antimalarial activities.Synthetic compounds from an in house library as inhibitors of falcipain-2 from Plasmodium falciparum.Artemisinin effectiveness in erythrocytes is reduced by heme and heme-containing proteins.Plasmodium serine hydroxymethyltransferase as a potential anti-malarial target: inhibition studies using improved methods for enzyme production and assayWhole-genome analysis reveals molecular innovations and evolutionary transitions in chromalveolate species.Probing the structure of falcipain-3, a cysteine protease from Plasmodium falciparum: comparative protein modeling and docking studies.Prodrugs of bisthiazolium salts are orally potent antimalarialsNovel antimalarial drug targets: hope for new antimalarial drugs.Microwave Assisted Synthesis of Pyrimidines in Ionic Liquid and Their Potency as Non-Classical Malarial Antifolates.5HT1A serotonin receptor agonists inhibit Plasmodium falciparum by blocking a membrane channel.In vivo antimalarial activities of mono- and bis quaternary ammonium salts interfering with Plasmodium phospholipid metabolismScreening extracts of Madagascan plants in search of antiplasmodial compounds.Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum.Anti-plasmodial and Chloroquine Resistance Suppressive Effects of EmbelinFolding of the Plasmodium falciparum cysteine protease falcipain-2 is mediated by a chaperone-like peptide and not the prodomain.Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum.Independent intramolecular mediators of folding, activity, and inhibition for the Plasmodium falciparum cysteine protease falcipain-2.Metal-free synthesis of N-fused heterocyclic iodides via C-H functionalization mediated by tert-butylhydroperoxide.Formation of catalytically active cross-species heterodimers of thymidylate synthase from Plasmodium falciparum and Plasmodium vivax.Development of antitrypanosomal and antiplasmodial nonpeptidic cysteine protease inhibitors based on N-protected-guanidino-furan and -pyrrole building blocks.Diarylpyrazole Ligated Dihydropyrimidine Hybrids as Potent Non-Classical Antifolates and Their Efficacy Against Plasmodium falciparum.Quantitative proteomics of Trypanosoma cruzi during metacyclogenesis.
P2860
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P2860
An overview of chemotherapeutic targets for antimalarial drug discovery.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
An overview of chemotherapeutic targets for antimalarial drug discovery.
@ast
An overview of chemotherapeutic targets for antimalarial drug discovery.
@en
An overview of chemotherapeutic targets for antimalarial drug discovery.
@nl
type
label
An overview of chemotherapeutic targets for antimalarial drug discovery.
@ast
An overview of chemotherapeutic targets for antimalarial drug discovery.
@en
An overview of chemotherapeutic targets for antimalarial drug discovery.
@nl
prefLabel
An overview of chemotherapeutic targets for antimalarial drug discovery.
@ast
An overview of chemotherapeutic targets for antimalarial drug discovery.
@en
An overview of chemotherapeutic targets for antimalarial drug discovery.
@nl
P1476
An overview of chemotherapeutic targets for antimalarial drug discovery.
@en
P2093
Olliaro PL
Yuthavong Y
P304
P356
10.1016/S0163-7258(98)00036-9
P577
1999-02-01T00:00:00Z