A common biological mechanism in cancer and Alzheimer's disease? - Test2 - elhamkhani - TriplyDB

A common biological mechanism in cancer and Alzheimer's disease?

A common biological mechanism in cancer and Alzheimer's disease?

http://www.wikidata.org/entity/Q33606991

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Gene Prioritization for Imaging Genetics Studies Using Gene Ontology and a Stratified False Discovery Rate Approach Diametrical diseases reflect evolutionary-genetic tradeoffs: Evidence from psychiatry, neurology, rheumatology, oncology and immunology Is neurodegenerative disease a long-latency response to early-life genotoxin exposure?The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner Unraveling 50-Year-Old Clues Linking Neurodegeneration and Cancer to Cycad Toxins: Are microRNAs Common Mediators?Chronic disease in men with newly diagnosed cancer: a nested case-control study Molecular evidence for the inverse comorbidity between central nervous system disorders and cancers detected by transcriptomic meta-analyses Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1 Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation.En1 and Wnt signaling in midbrain dopaminergic neuronal development.Cancer and neurodegeneration: between the devil and the deep blue sea.Folate deficiency exacerbates apoptosis by inducing hypomethylation and resultant overexpression of DR4 together with altering DNMTs in Alzheimer's disease.Autism and cancer risk.Association of cancer history with Alzheimer's disease onset and structural brain changes.Inverse correlation between Alzheimer's disease and cancer: implication for a strong impact of regenerative propensity on neurodegeneration?BRCA1 and p53 tumor suppressor molecules in Alzheimer's disease.Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia severity.Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice.Inverse relationship between cancer and Alzheimer's disease: a systemic review meta-analysis.Network Comparison of Inflammation in Colorectal Cancer and Alzheimer's Disease.Inverse susceptibility to oxidative death of lymphocytes obtained from Alzheimer's patients and skin cancer survivors: increased apoptosis in Alzheimer's and reduced necrosis in cancer.Non-melanoma skin cancer and risk of Alzheimer's disease and all-cause dementia.PathNet: a tool for pathway analysis using topological information The inverse association of cancer and Alzheimer's: a bioenergetic mechanism.Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling.Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study Transcriptional signaling pathways inversely regulated in Alzheimer's disease and glioblastoma multiform.Nonmelanoma skin cancer is associated with reduced Alzheimer disease risk.Associations between cancer and Alzheimer's disease in a U.S. Medicare population.Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways.Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer's Disease.T-cell factor/β-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease.DNA methylation as a universal biomarker.Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease.The senescence hypothesis of disease progression in Alzheimer disease: an integrated matrix of disease pathways for FAD and SAD.Inverse association between cancer and neurodegenerative disease: review of the epidemiologic and biological evidence.Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease.Differences of immune disorders between Alzheimer's disease and breast cancer based on transcriptional regulation.Interaction of Aβ peptide with tubulin causes an inhibition of tubulin polymerization and the apoptotic death of cancer cells.

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P2860

A common biological mechanism in cancer and Alzheimer's disease?

http://www.wikidata.org/entity/Q33606991

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2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年论文

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A common biological mechanism in cancer and Alzheimer's disease?

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A common biological mechanism in cancer and Alzheimer's disease?

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Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

Alzheimer Disease and Mortality

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP

The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production

Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

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