Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase. - Test2 - elhamkhani - TriplyDB

Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.

Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.

http://www.wikidata.org/entity/Q37764617

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Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogaster HYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer Response LITAF and TNFSF15, two downstream targets of AMPK, exert inhibitory effects on tumor growth Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species.Zfra is a small wizard in the mitochondrial apoptosis miR-134 induces oncogenicity and metastasis in head and neck carcinoma through targeting WWOX gene.WW domain-containing oxidoreductase in neuronal injury and neurological diseases.Identification of an In Vivo MEK/WOX1 Complex as a Master Switch for Apoptosis in T Cell Leukemia.Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain.Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.Emerging roles for hyaluronidase in cancer metastasis and therapy.HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program for mesenchymal-epithelial transition in bone metastatic versus parental breast carcinoma cells TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death Role of WWOX and NF-κB in lung cancer progression Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase WWOX dysfunction induces sequential aggregation of TRAPPC6AΔ, TIAF1, tau and amyloid β, and causes apoptosis.The supposed tumor suppressor gene WWOX is mutated in an early lethal microcephaly syndrome with epilepsy, growth retardation and retinal degeneration.Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed.The fragile site WWOX gene and the developing brain.Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors.Zfra induction of memory anticancer response via a novel immune cell Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation.Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation.Reduced WWOX protein expression in human astrocytoma.Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events.WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.WWOX Phosphorylation, Signaling, and Role in Neurodegeneration

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Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.

http://www.wikidata.org/entity/Q37764617

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 11 June 2010

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Signaling from membrane recept ...... ain-containing oxidoreductase.

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Signaling from membrane recept ...... ain-containing oxidoreductase.

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type

label

Signaling from membrane recept ...... ain-containing oxidoreductase.

@en

Signaling from membrane recept ...... ain-containing oxidoreductase.

@nl

prefLabel

Signaling from membrane recept ...... ain-containing oxidoreductase.

@en

Signaling from membrane recept ...... ain-containing oxidoreductase.

@nl

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EBM.2010.009351

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Experimental Biology and Medicine

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Signaling from membrane recept ...... ain-containing oxidoreductase.

@en

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Feng-Jie Lai

http://www.w3.org/2001/XMLSchema#string

Hsin-Ping Lin

http://www.w3.org/2001/XMLSchema#string

Jean-Yun Chang

http://www.w3.org/2001/XMLSchema#string

Li-Jin Hsu

http://www.w3.org/2001/XMLSchema#string

Nan-Shan Chang

http://www.w3.org/2001/XMLSchema#string

Qunying Hong

http://www.w3.org/2001/XMLSchema#string

Ruei-Yu He

http://www.w3.org/2001/XMLSchema#string

Shean-Jen Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response

Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer

WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function

Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins

WW domains provide a platform for the assembly of multiprotein networks

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog

Targeted deletion of Wwox reveals a tumor suppressor function

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scholarly article

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10.1258/EBM.2010.009351

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