The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.
about
The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancersBRCA1 and estrogen/estrogen receptor in breast cancer: where they interact?RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisRANKL/RANK: from bone loss to the prevention of breast cancerIntegrity of the LXXLL motif in Stat6 is required for the inhibition of breast cancer cell growth and enhancement of differentiation in the context of progesterone.Cell surface sialylation and fucosylation are regulated by L1 via phospholipase Cgamma and cooperate to modulate neurite outgrowth, cell survival and migration.Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.Progesterone and breast cancer.Progesterone receptor isoform functions in normal breast development and breast cancerDecreased progesterone receptor isoform expression in luteal phase fallopian tube epithelium and high-grade serous carcinomaSmall-molecule "BRCA1-mimetics" are antagonists of estrogen receptor-αActivation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer.Regulation of progesterone receptor signaling by BRCA1 in mammary cancer.Altered AIB1 or AIB1Δ3 expression impacts ERα effects on mammary gland stromal and epithelial contentAssessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models.Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.Progesterone regulation of stem and progenitor cells in normal and malignant breastA new class of small molecule estrogen receptor-alpha antagonists that overcome anti-estrogen resistance.The biology of progesterone receptor in the normal mammary gland and in breast cancerAKT regulates BRCA1 stability in response to hormone signaling.BRCA1 deficient mouse models to study pathogenesis and therapy of triple negative breast cancer.Growth arrest-specific gene 6 expression in human breast cancer.Challenges to defining a role for progesterone in breast cancer.BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancerBRCA1, hormone, and tissue-specific tumor suppressionEndocrinology of the wild and mutant BRCA1 gene and types of hormonal carcinogenesis.A composite intronic element directs dynamic binding of the progesterone receptor and GATA-2.Mechanism of BRCA1-mediated inhibition of progesterone receptor transcriptional activityRANKL/RANK control Brca1 mutation-driven mammary tumors.BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage.Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini.Proliferation and ovarian hormone signaling are impaired in normal breast tissues from women with BRCA1 mutations: benefit of a progesterone receptor modulator treatment as a breast cancer preventive strategy in women with inherited BRCA1 mutations.Synthesis, spectral characterization, and in vitro cellular activities of metapristone, a potential cancer metastatic chemopreventive agent derived from mifepristone (RU486).Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.Mouse models of BRCA1 and their application to breast cancer research.GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells.Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue.A unified method for purification of basic proteinsCell surface sialylation and fucosylation are regulated by the cell recognition molecule L1 via PLCgamma and cooperate to modulate embryonic stem cell survival and proliferation.
P2860
Q21260410-208ED993-222F-4BF9-994B-A01415649A2DQ26822737-062E136D-8C28-4A20-9E79-128E90EE8E7CQ26853207-8893D0AD-6A63-49C2-B5F4-31B3553224EDQ28075004-8B19D5F4-D47F-4489-BE3D-FFCEEDCE9F78Q30578094-9D2D5150-8DDB-4C4C-9588-657C26F1A4A1Q33388707-817A22D2-5980-4406-B5FA-65F20F2CEF93Q33569159-C28E8249-9955-426B-ADA8-1B3E5D3A5710Q33576505-D7F7590D-A682-437D-BDC5-75A20A2E8A66Q33687459-AEFB4A29-378B-4803-8367-68C04AE8C7DFQ33693898-BE4F3C82-3952-4ACC-BB98-1607E3B854CFQ34595670-6925A239-22BD-4B0A-AC3F-E725A0234EDCQ34603057-197BF51C-F989-4942-8B2C-B7D9C29EA37AQ34609774-054A980F-128D-4E63-9290-EE6D76A28B54Q34652156-98CB4D50-00E3-4F0C-B966-16CC24971924Q34712100-E3BF09D1-F6D4-419F-B523-A83B53B51F68Q35157919-2D3A2704-613E-47C6-9FB0-CA7A8D36B20DQ35749504-A126AC9E-D0DE-4DEF-B560-BABA41A2102CQ35784828-C194998A-B115-4EC7-BA41-CAA329743AF0Q35843483-EAB31F72-A225-46C6-A9E8-ACFFA80A7299Q35868802-B482D4BE-3D05-4520-9A06-D8B5A88278B1Q35994422-E745BE5D-456A-4AE6-BC37-C123ED19F343Q36406519-CA5954AF-4151-476A-82DA-5FF042AD4733Q36510114-FAA26816-EF99-451B-B349-DB3ADF7740E6Q36786766-D693759B-202D-4303-AD6C-1095C9323AACQ36838404-FF031C1E-270D-437F-80B6-0BAFF977C96AQ37020551-AF302AF5-FE18-4B5B-A9F6-188A08011C19Q37074121-3B4496FE-13B7-4076-A6EC-D15714B511E5Q37106835-FFA05D50-5095-476C-81BF-80E789677A1CQ37283603-1124D5E3-BD94-432D-9DC5-93F200521B79Q37457304-626A9CA3-43AF-4EDF-8567-B494E892C81BQ37479248-B01D6877-F219-4846-BD9A-DE91491CFBDFQ37541638-687F3800-AF82-4CE7-9085-21BB389B78F2Q37564411-FF27FD50-6EB8-45E9-AC00-73F15FF9B698Q37601043-C5860DC1-DD1B-42BD-88B8-CB0386FFBADBQ37933098-DBB99B46-3023-4F34-B3B8-201DB17654A9Q38055069-0D013EB4-9B5A-4F5B-9D64-60F6440471D4Q38291863-3F608642-CDF4-42AA-9DB3-D2A7A262EE2BQ39069405-2F1B8D0E-B78A-4A49-96CF-4E4DA70F13D6Q41895529-C360140A-A38D-4062-AC90-EE08D341593EQ42803940-F36793D5-AD5B-40B8-AAEB-11FBF3D9E038
P2860
The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The breast cancer susceptibili ...... g in mammary epithelial cells.
@ast
The breast cancer susceptibili ...... g in mammary epithelial cells.
@en
type
label
The breast cancer susceptibili ...... g in mammary epithelial cells.
@ast
The breast cancer susceptibili ...... g in mammary epithelial cells.
@en
prefLabel
The breast cancer susceptibili ...... g in mammary epithelial cells.
@ast
The breast cancer susceptibili ...... g in mammary epithelial cells.
@en
P2093
P2860
P356
P1476
The breast cancer susceptibili ...... g in mammary epithelial cells.
@en
P2093
Eliot M Rosen
Laundette P Jones
Pragati Katiyar
Priscilla A Furth
Saijun Fan
Yiyu Zhang
Yongxian Ma
P2860
P356
10.1210/ME.2004-0488
P577
2005-08-18T00:00:00Z