Global consequences of activation loop phosphorylation on protein kinase A. - Test2 - elhamkhani - TriplyDB

Global consequences of activation loop phosphorylation on protein kinase A.

Global consequences of activation loop phosphorylation on protein kinase A.

http://www.wikidata.org/entity/Q33662139

about

PKA: lessons learned after twenty years Assembly of allosteric macromolecular switches: lessons from PKA A Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase Fold Structural Basis for the Regulation of Protein Kinase A by Activation Loop Phosphorylation Role of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein Kinase Promotion of Enzyme Flexibility by Dephosphorylation and Coupling to the Catalytic Mechanism of a Phosphohexomutase cAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometry Protein kinases: evolution of dynamic regulatory proteins Structural dynamic analysis of apo and ATP-bound IRAK4 kinase Regulation of cAMP-dependent protein kinases: the human protein kinase X (PrKX) reveals the role of the catalytic subunit alphaH-alphaI loop.Dynamic architecture of a protein kinase.Phosphorylation in the catalytic cleft stabilizes and attracts domains of a phosphohexomutase Carboxyl-group footprinting maps the dimerization interface and phosphorylation-induced conformational changes of a membrane-associated tyrosine kinase.Regulation of protein kinase D1 activity.Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase Molecular Dynamics Simulations and Classical Multidimensional Scaling Unveil New Metastable States in the Conformational Landscape of CDK2.Phosphodiesterase 4D acts downstream of Neuropilin to control Hedgehog signal transduction and the growth of medulloblastoma Evolution of the eukaryotic protein kinases as dynamic molecular switches.An Allosteric Cross-Talk Between the Activation Loop and the ATP Binding Site Regulates the Activation of Src Kinase.O-GlcNAcylation of protein kinase A catalytic subunits enhances its activity: a mechanism linked to learning and memory deficits in Alzheimer's disease.Human heart failure is accompanied by altered protein kinase A subunit expression and post-translational state.HDX-MS takes centre stage at unravelling kinase dynamics.A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus.OGlcNAcylation and phosphorylation have opposing structural effects in tau: phosphothreonine induces particular conformational order.OGlcNAcylation and phosphorylation have similar structural effects in α-helices: post-translational modifications as inducible start and stop signals in α-helices, with greater structural effects on threonine modification.Saccharomyces cerevisiae Env7 is a novel serine/threonine kinase 16-related protein kinase and negatively regulates organelle fusion at the lysosomal vacuole.Integration of signaling in the kinome: Architecture and regulation of the αC Helix.Kinase regulation by hydrophobic spine assembly in cancer.Suppression of Zika virus infection and replication in endothelial cells and astrocytes by PKA inhibitor PKI 14-22.In silico evaluation of the resistance of the T790M variant of epidermal growth factor receptor kinase to cancer drug Erlotinib.Decreased autophagy induced by β1-adrenoceptor autoantibodies contributes to cardiomyocyte apoptosis.A Gaussian network model study suggests that structural fluctuations are higher for inactive states than active states of protein kinases.The activation loop of PKA catalytic isoforms is differentially phosphorylated by Pkh protein kinases in Saccharomyces cerevisiae.

P2860

Q26823926-E76A830C-55FC-447F-9E60-F9CFC4DFCE0E Q26852228-BA331187-AAB3-4A29-8100-0076B66F656E Q27675934-F6D47433-479C-48EF-A9F5-24B10A0EB08E Q27677271-CCB3BD96-3EC9-4041-8599-C0F6200AE1CD Q27679248-7377A001-29B4-4566-B53C-8E0E86F053D9 Q27681238-7FC4EEAB-D206-4054-83DA-CA2FE5F1AF03 Q28822154-8034F2C4-03F8-4BF6-B6E6-8BAFD9A37859 Q30014836-C091C801-86F4-4B55-B008-10C429675035 Q30584224-5F472930-CE0E-4AD2-B948-42257300D6A1 Q34285354-8CB2B8E5-BD79-4B12-8224-CF941F558DB1 Q34442244-AA9B58B4-6C87-4955-8524-B1CBA20D1D2B Q34996616-2581C2D2-4B33-4DC0-B89C-687ADAFF5FAC Q35026889-C24591F8-6ED3-4F0F-A45E-4A7B9DA55F24 Q35776742-D294A2D5-8545-49DB-9EB1-949714951939 Q35974030-4A8E7B11-0094-482C-BCEA-AB085F8D1976 Q35995752-7A41E043-0048-4C7D-B3B8-4BD0A2C16839 Q36059854-B0B4CA88-C573-4B7D-BB2E-2C64F741C2DD Q36153870-A6F54051-9C81-4F9C-8248-8161533C6B42 Q36785393-6BE73613-FC9C-429C-8D7C-4FAC51E9DB1B Q36863783-D2D83962-6376-4AD8-85AF-3EA812149804 Q37427881-A38F76D1-54D9-4D92-9E67-2D7805CE7CD2 Q38180771-5BFC73F0-EB11-4F57-A816-57EF86F5528C Q38760185-1B00E0D2-61C5-4C61-B006-6A7AFD628395 Q39045088-9ABFF28B-63A8-4903-B06A-94A977F4918E Q39045464-D689C49C-DFF0-4EE4-B936-9F2253F6667F Q42059939-CE200A2B-839D-4D21-8DB4-A384FAC2F412 Q42152183-A6FD826C-7DDF-4ACB-AE28-64EA4EFEAA2B Q43107147-89BFEA86-6D28-41FE-806C-5E5EFAE6C584 Q45323705-D333AB7E-96D6-4EA5-9883-E5B83C248708 Q47355906-1B415FAD-012A-4977-9FD2-C28FD6D82D79 Q51740123-65C1C1AA-F769-476F-87EC-00E681D475A1 Q53624405-3A8427F5-411F-454E-A125-4E44E68062C3 Q54485555-7B543D1D-302F-4CBE-AAF3-955B5D87F49C

P2860

Global consequences of activation loop phosphorylation on protein kinase A.

http://www.wikidata.org/entity/Q33662139

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Global consequences of activation loop phosphorylation on protein kinase A.

@ast

Global consequences of activation loop phosphorylation on protein kinase A.

@en

type

label

Global consequences of activation loop phosphorylation on protein kinase A.

@ast

Global consequences of activation loop phosphorylation on protein kinase A.

@en

prefLabel

Global consequences of activation loop phosphorylation on protein kinase A.

@ast

Global consequences of activation loop phosphorylation on protein kinase A.

@en

P1433

Q33662139-2753467D-5631-4A80-BC21-A77F45235173

P1476

Q33662139-25FD3719-F8B1-405F-B7D6-1F6BA37CF4C2

P2093

Q33662139-09244A84-2AFA-4A07-8CAD-1923F2521EF7

Q33662139-0F2D2BF0-1A5D-4CD2-9824-E3818026C8C1

Q33662139-6FFF150D-D355-4544-8702-92A433164371

Q33662139-882F85C2-0CE6-4E01-BB48-61066ED04B3E

Q33662139-9562E3BC-479E-43EF-AFCC-1C7722169F50

Q33662139-E4128659-500E-4A35-BA03-54171631D133

Q33662139-F2D02041-8467-496F-8D3C-AA54218F820B

P2860

Q33662139-00E8AA1C-A94E-48EA-B703-5019D96131DE

Q33662139-0DE35AA9-9CF3-4729-971C-AFC296F03F59

Q33662139-15E5881E-6A11-47B8-A0DD-49FB22DDE40A

Q33662139-1817A58A-DA56-4D52-8F28-60B2E2982C71

Q33662139-1DE98A89-9102-4FC3-99C9-739974017D46

Q33662139-1EDC8DEE-16A8-4353-A43A-659063210196

Q33662139-27E4033B-792F-43CE-BFE6-873A7DFDF288

Q33662139-36B80932-13C7-4673-AF25-6ADCC8B06BD3

Q33662139-45A16A33-E519-4F59-837C-CA2C2B4CF636

Q33662139-55191E41-7C84-489C-8AB4-266AA608B307

P304

Q33662139-C514089E-19D6-489B-A74D-F04DE1B4CD0A

P31

Q33662139-B6F2A4A1-5AE2-4BAD-94CC-3B0F94E4C280

P356

Q33662139-D74A0C38-21D1-40D6-988C-EA1CB2A240F6

P407

Q33662139-FF3484D0-9C1C-4DD1-8A71-AB10872683BA

P433

Q33662139-ACB033BF-0D3E-4BEE-97A6-445E6E318CF8

P478

Q33662139-EDE144B9-BD48-4EAB-AD97-8FB3203643BD

P577

Q33662139-DC5AFA31-5C35-4444-A797-B598F89F20F5

P5875

Q33662139-ADD5CCE1-7B46-405B-B4A0-BCF707941194

P698

Q33662139-0A1595B3-466E-4E3D-BAAA-C781CA5C1A92

P921

Q33662139-7B86B90D-F615-4503-B444-5B102BF17206

P932

Q33662139-E15FDB72-A248-4B5B-855B-754B88F715F8

P356

JBC.M109.061820

P1433

Journal of Biological Chemistry

P1476

Global consequences of activation loop phosphorylation on protein kinase A.

@en

P2093

Ganesh H Iyer

http://www.w3.org/2001/XMLSchema#string

Jon M Steichen

http://www.w3.org/2001/XMLSchema#string

Michael S Deal

http://www.w3.org/2001/XMLSchema#string

S Adrian Saldanha

http://www.w3.org/2001/XMLSchema#string

Sheng Li

http://www.w3.org/2001/XMLSchema#string

Susan S Taylor

http://www.w3.org/2001/XMLSchema#string

Virgil L Woods

http://www.w3.org/2001/XMLSchema#string

P2860

Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

Crystal structure of aurora-2, an oncogenic serine/threonine kinase

Crystal structure of an inactive Akt2 kinase domain

Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure

Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

Crystal structure of domain-swapped STE20 OSR1 kinase domain

A Src-like inactive conformation in the abl tyrosine kinase domain

Determination and analysis of urea and guanidine hydrochloride denaturation curves

Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

P304

3825-3832

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M109.061820

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

285

http://www.w3.org/2001/XMLSchema#string

P577

2009-12-04T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

40452839

http://www.w3.org/2001/XMLSchema#string

P698

19965870

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

2823524

http://www.w3.org/2001/XMLSchema#string