HDX-MS takes centre stage at unravelling kinase dynamics.

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HDX-MS takes centre stage at unravelling kinase dynamics.

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HDX-MS takes centre stage at unravelling kinase dynamics.

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HDX-MS takes centre stage at unravelling kinase dynamics.

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HDX-MS takes centre stage at unravelling kinase dynamics.

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P1476

HDX-MS takes centre stage at unravelling kinase dynamics.

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P2093

Kristina Lorenzen

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Tony Pawson

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P2860

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design

Partial cooperative unfolding in proteins as observed by hydrogen exchange mass spectrometry.

Native state dynamics drive the unfolding of the SH3 domain of PI3 kinase at high denaturant concentration.

Partial unfolding of diverse SH3 domains on a wide timescale.

Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins.

Conformational disturbance in Abl kinase upon mutation and deregulation.

Global consequences of activation loop phosphorylation on protein kinase A.

Drug binding and resistance mechanism of KIT tyrosine kinase revealed by hydrogen/deuterium exchange FTICR mass spectrometry.

P304

145-150

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P31

scholarly article

P356

10.1042/BST20130250

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P433

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P478

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P577

2014-02-01T00:00:00Z

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P698

24450642

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