Ubiquitylation of a melanosomal protein by HECT-E3 ligases serves as sorting signal for lysosomal degradation.
about
The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and compositionThe E3 ubiquitin ligase Itch regulates sorting nexin 9 through an unconventional substrate recognition domainThe tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesisNedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cellsNedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cellsMelanosomes--dark organelles enlighten endosomal membrane transportHermansky-Pudlak syndrome: a disease of protein trafficking and organelle function.Just one position-independent lysine residue can direct MelanA into proteasomal degradation following N-terminal fusion of ubiquitin.Versatile roles of k63-linked ubiquitin chains in trafficking.The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) functionA lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis.Mechanisms of protein delivery to melanosomes in pigment cells.A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sortingThe Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.Ubiquitylation of ion channels.ESCRT-I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane.FIG4, Charcot-Marie-Tooth disease, and hypopigmentation: a role for phosphoinositides in melanosome biogenesis?Cancer driver-passenger distinction via sporadic human and dog cancer comparison: a proof-of-principle study with colorectal cancer.Protein quality control system in neurodegeneration: a healing company hard to beat but failure is fatal.Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity.The E3 ligase Itch in immune regulation and beyond.The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.HECT-type ubiquitin ligase ITCH targets lysosomal-associated protein multispanning transmembrane 5 (LAPTM5) and prevents LAPTM5-mediated cell death.Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases.Recognition mechanism of p63 by the E3 ligase Itch: novel strategy in the study and inhibition of this interactionA mart-1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium.Biogenesis of Melanosomes
P2860
Q24311263-55014BE5-8500-40AE-ABAF-A3EC00EC525AQ24314485-3A67EAB9-4E94-4585-9488-BD69C9774C27Q24338990-11FC2DB1-8E68-4C33-AEFD-589F5EB9C555Q24615775-72B4F607-24A6-4E36-86DD-F9944A18667FQ24644225-F8C76E8F-C13E-4A25-A1A3-E48E3B918560Q24647195-603745BC-155F-487A-81D8-8D98BD63C2F9Q34485728-5855ACBD-E068-442E-AA46-C55ADD010E15Q34581001-AEDA9220-7725-4A57-9119-B8273F64C13BQ34774715-1DE2A67E-BBA7-4460-A8B0-BC61F11D6F68Q35123182-80CFB129-7E32-430B-B683-850F9C727398Q35594079-F23C225F-6743-41BF-A0A4-F4E61806E2A7Q35936316-1364AA00-CC1A-48E7-A77B-737D524C9A70Q35998598-08E3AB70-6FED-457D-8795-8229D730A1E8Q36257261-2182EA6A-FD1E-4CF0-9387-9164E7730D83Q36313080-285F1464-33A7-47F6-88A7-26F1DC64EE01Q37354349-D1706662-D8BF-4FC1-915E-014DEB852C7BQ37412247-38F8863E-DB8F-4784-B852-39DB2EFD49FEQ37598464-8831CFD0-B2D9-40E6-AEA4-D931396615FDQ38078868-61348093-0694-46DC-A8B2-012A4A1311E7Q38314921-B0D57546-B2D4-4929-B2FF-6634CB03336AQ38530613-6B5CC12E-FFB2-4A7C-845C-EEFCA980D82FQ38793501-8F9197FF-AF7B-4133-99D6-67BFBA0221ABQ39456149-29CFA23A-E9E7-4DFF-A749-32EF49F8C1D2Q41851754-7B043C41-E3BB-4F84-8A13-5FF82238E3FBQ42270113-06B8EB21-847C-4CB8-89CD-924010E7453AQ51889124-AE6A9F6B-FF80-4384-8F5F-6265456423BBQ58450115-67514D9D-7390-4CEC-BAB0-EBECE5A44499
P2860
Ubiquitylation of a melanosomal protein by HECT-E3 ligases serves as sorting signal for lysosomal degradation.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Ubiquitylation of a melanosoma ...... nal for lysosomal degradation.
@ast
Ubiquitylation of a melanosoma ...... nal for lysosomal degradation.
@en
type
label
Ubiquitylation of a melanosoma ...... nal for lysosomal degradation.
@ast
Ubiquitylation of a melanosoma ...... nal for lysosomal degradation.
@en
prefLabel
Ubiquitylation of a melanosoma ...... nal for lysosomal degradation.
@ast
Ubiquitylation of a melanosoma ...... nal for lysosomal degradation.
@en
P2093
P2860
P356
P1476
Ubiquitylation of a melanosoma ...... nal for lysosomal degradation.
@en
P2093
Anne-Lise Peitrequin
Cecilia K Lindholm
Donata Rimoldi
Frédéric Lévy
Jean-Charles Cerottini
Katja Muehlethaler
Suzanne Salvi
P2860
P304
P356
10.1091/MBC.E04-09-0803
P577
2005-02-09T00:00:00Z