Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
about
Staphylococcus aureus α-hemolysin mediates virulence in a murine model of severe pneumonia through activation of the NLRP3 inflammasomeRole of the inflammasome, IL-1β, and IL-18 in bacterial infectionsFighting the Monster: Applying the Host Damage Framework to Human Central Nervous System InfectionsBacterial Exotoxins and the InflammasomeInflammasome/IL-1β Responses to Streptococcal PathogensInsights into phagocytosis-coupled activation of pattern recognition receptors and inflammasomesNOD-Like Receptors: Master Regulators of Inflammation and CancerRegulation of inflammasome signalingRecognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive ImmunityRole of non-conventional T lymphocytes in respiratory infections: the case of the pneumococcusCirculating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal InfectionT regulatory cells control susceptibility to invasive pneumococcal pneumonia in miceThe host immune dynamics of pneumococcal colonization: implications for novel vaccine developmentInflammasomes: caspase-1-activating platforms with critical roles in host defenseRegulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung DiseaseOverview of community-acquired pneumonia and the role of inflammatory mechanisms in the immunopathogenesis of severe pneumococcal disease.Type I interferon signaling regulates activation of the absent in melanoma 2 inflammasome during Streptococcus pneumoniae infection.Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.Natural Killer Cell Functions during the Innate Immune Response to Pathogenic Streptococci.The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent.Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced diseaseVisualization of murine intranasal dosing efficiency using luminescent Francisella tularensis: effect of instillation volume and form of anesthesia.Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function.TLR-mediated inflammatory responses to Streptococcus pneumoniae are highly dependent on surface expression of bacterial lipoproteinsPolymyxin B inadequately quenches the effects of contaminating lipopolysaccharide on murine dendritic cells.Role of pore-forming toxins in bacterial infectious diseases.Immune receptors involved in Streptococcus suis recognition by dendritic cells.Current concepts in host-microbe interaction leading to pneumococcal pneumoniaExperimental human pneumococcal carriage augments IL-17A-dependent T-cell defence of the lung.Designed reduction of Streptococcus pneumoniae pathogenicity via synthetic changes in virulence factor codon-pair biasHost response and bacterial virulence factor expression in Pseudomonas aeruginosa and Streptococcus pneumoniae corneal ulcers.ADP-ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity.Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1β - A Possible Pathway of Exacerbations in COPDInflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis.Inflammasomes.Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tractInnate immunity and transplantation tolerance: the potential role of TLRs/NLRs in GVHDInflammasome activation in response to the Yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD.The pneumococcal polysaccharide capsule and pneumolysin differentially affect CXCL8 and IL-6 release from cells of the upper and lower respiratory tractNeutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
P2860
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P2860
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Pneumolysin activates the NLRP ...... tokines independently of TLR4.
@ast
Pneumolysin activates the NLRP ...... tokines independently of TLR4.
@en
type
label
Pneumolysin activates the NLRP ...... tokines independently of TLR4.
@ast
Pneumolysin activates the NLRP ...... tokines independently of TLR4.
@en
prefLabel
Pneumolysin activates the NLRP ...... tokines independently of TLR4.
@ast
Pneumolysin activates the NLRP ...... tokines independently of TLR4.
@en
P2093
P2860
P50
P1433
P1476
Pneumolysin activates the NLRP ...... ytokines independently of TLR4
@en
P2093
Aine Burke
Andres Mori
Cathy Baxter
Daniela Ferreira
Edel A McNeela
Jurg Tschopp
Katherine A Fitzgerald
Peter W Andrew
Rana El-Rachkidy
Sarah Smeaton
P2860
P304
P356
10.1371/JOURNAL.PPAT.1001191
P577
2010-11-11T00:00:00Z