The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.
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Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism.Not all J domains are created equal: implications for the specificity of Hsp40-Hsp70 interactionsNMR structure of the N-terminal J domain of murine polyomavirus T antigens. Implications for DnaJ-like domains and for mutations of T antigensStructural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigenA mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding proteinMolecular determinants for the complex formation between the retinoblastoma protein and LXCXE sequencesThe cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activityCytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding siteA Strategy for Direct Chemical Activation of the Retinoblastoma ProteinThe SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53.Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain.Chaperones in cell cycle regulation and mitogenic signal transduction: a review.Enumeration of the simian virus 40 early region elements necessary for human cell transformationInduction of interferon-stimulated genes by Simian virus 40 T antigens.Regions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts.Biological activities and molecular targets of the human papillomavirus E7 oncoprotein.Transforming functions of Simian Virus 40.Interactions of SV40 large T antigen and other viral proteins with retinoblastoma tumour suppressor.T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisRB and cyclin dependent kinase pathways: defining a distinction between RB and p16 loss in lung cancer.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Simian virus 40 large T antigen and two independent T-antigen segments sensitize cells to apoptosis following genotoxic damageInhibition of post-transcriptional RNA processing by CDK inhibitors and its implication in anti-viral therapy.The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progressionSestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.Cross-talk between T-Ag presence and pRb family and p53/p73 signaling in mouse and human medulloblastoma.Id2 deficiency promotes metastasis in a mouse model of ocular cancer.Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigenHighly invasive transitional cell carcinoma of the bladder in a simian virus 40 T-antigen transgenic mouse modelTruncated N-terminal mutants of SV40 large T antigen as minimal immortalizing agents for CNS cellsEnterocyte proliferation and intestinal hyperplasia induced by simian virus 40 T antigen require a functional J domainArrest of mammalian fibroblasts in G1 in response to actin inhibition is dependent on retinoblastoma pocket proteins but not on p53Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.Simian virus 40 T antigens and J domains: analysis of Hsp40 cochaperone functions in Escherichia coli.The conserved core enzymatic activities and the distinct dynamics of polyomavirus large T antigensRegulation of the retinoblastoma proteins by the human herpesviruses.
P2860
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P2860
The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The J domain of simian virus 4 ...... inactivate RB family proteins.
@ast
The J domain of simian virus 4 ...... inactivate RB family proteins.
@en
type
label
The J domain of simian virus 4 ...... inactivate RB family proteins.
@ast
The J domain of simian virus 4 ...... inactivate RB family proteins.
@en
prefLabel
The J domain of simian virus 4 ...... inactivate RB family proteins.
@ast
The J domain of simian virus 4 ...... inactivate RB family proteins.
@en
P2860
P356
P1476
The J domain of simian virus 4 ...... inactivate RB family proteins
@en
P2093
J A DeCaprio
P2860
P304
P356
10.1128/MCB.18.3.1408
P407
P50
P577
1998-03-01T00:00:00Z