Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
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The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleMutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteinspRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4FTelomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumorsHuman CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.Binding of an interferon-inducible protein (p202) to the retinoblastoma proteinE2F-6, a member of the E2F family that can behave as a transcriptional repressorGrowth suppression by p16ink4 requires functional retinoblastoma proteinBS69, a novel adenovirus E1A-associated protein that inhibits E1A transactivationThe retinoblastoma protein binds to a family of E2F transcription factorsA cellular repressor of E1A-stimulated genes that inhibits activation by E2FRNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130.Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulationNegative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7.Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism.Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcriptionCDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseJumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factorsThe consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2Structure and cell cycle-regulated transcription of the human cyclin A geneHuman cyclin FInteraction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivationGenetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid systemReverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactionsRegulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinasesGenomic structure of the human retinoblastoma-related Rb2/p130 geneCyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylationAnalysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repressionDP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivoThe three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylaseThe subcellular localization of E2F-4 is cell-cycle dependentE2F activity is regulated by cell cycle-dependent changes in subcellular localizationInduction of S-phase entry by E2F transcription factors depends on their nuclear localizationCyclin A expression is under negative transcriptional control during the cell cycleId2 specifically alters regulation of the cell cycle by tumor suppressor proteinsE2F-4 switches from p130 to p107 and pRB in response to cell cycle reentryAssociation of p107 with Sp1: genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcriptionDifferential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins
P2860
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P2860
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@ast
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@en
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@nl
type
label
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@ast
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@en
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@nl
altLabel
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
@ast
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.
@en
prefLabel
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@ast
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@en
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@nl
P2093
P3181
P356
P1433
P1476
Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein
@en
P2093
D Livingston
S van den Heuvel
P304
P3181
P356
10.1101/GAD.7.7A.1111
P407
P577
1993-07-01T00:00:00Z