mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response.
about
MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domainPrevention of cytokine withdrawal-induced apoptosis by Mcl-1 requires interaction between Mcl-1 and BimAn internal EELD domain facilitates mitochondrial targeting of Mcl-1 via a Tom70-dependent pathwayBcl2 Family Functions as Signaling Target in Nicotine-/NNK-Induced Survival of Human Lung Cancer Cells.Neutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and Fortilin. The potential role of MCL1 as a fortilin chaperoneStabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTPInhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expressionThr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancerGATA factors are essential for transcription of the survival gene E4bp4 and the viability response of interleukin-3 in Ba/F3 hematopoietic cellsEDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer.Modulation of Mcl-1 expression reduces age-related cochlear degenerationAge-related changes in the ratio of Mcl-1/Bax expression in the rat cochlea.Acoustic overstimulation modifies Mcl-1 expression in cochlear sensory epithelial cells.Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearanceBim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREBCytokine receptor common beta chain as a potential activator of cytokine withdrawal-induced apoptosis.Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor.CREB is one component of the binding complex of the Ces-2/E2A-HLF binding element and is an integral part of the interleukin-3 survival signal.Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis.Inhibition of translation by cytotrienin A--a member of the ansamycin familyCell metabolism: an essential link between cell growth and apoptosisMcl-1: a highly regulated cell death and survival controller.Over-expression of interleukin-6 enhances cell survival and transformed cell growth in human malignant cholangiocytes.The essential role of evasion from cell death in cancer.Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies.IL-32γ delays spontaneous apoptosis of human neutrophils through MCL-1, regulated primarily by the p38 MAPK pathway.Analysis of Cynandione A's Anti-Ischemic Stroke Effects from Pathways and Protein-Protein Interactome.The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophagesThe antiapoptotic protein Mcl-1 controls the type of cell death in Theiler's virus-infected BHK-21 cells.Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATPFKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity.Cytokines in the differentiation therapy of leukemia: from laboratory investigations to clinical applications.Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell deathBCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Leishmania donovani Exploits Myeloid Cell Leukemia 1 (MCL-1) Protein to Prevent Mitochondria-dependent Host Cell Apoptosis.Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia.The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.
P2860
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P2860
mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response.
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
mcl-1 is an immediate-early ge ...... the GM-CSF viability response.
@ast
mcl-1 is an immediate-early ge ...... the GM-CSF viability response.
@en
type
label
mcl-1 is an immediate-early ge ...... the GM-CSF viability response.
@ast
mcl-1 is an immediate-early ge ...... the GM-CSF viability response.
@en
prefLabel
mcl-1 is an immediate-early ge ...... the GM-CSF viability response.
@ast
mcl-1 is an immediate-early ge ...... the GM-CSF viability response.
@en
P2093
P2860
P356
P1476
mcl-1 is an immediate-early ge ...... the GM-CSF viability response.
@en
P2093
H F Yang-Yen
P2860
P304
P356
10.1128/MCB.18.8.4883
P407
P577
1998-08-01T00:00:00Z