FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity.
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Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic functionSilent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activityPrevention of cytokine withdrawal-induced apoptosis by Mcl-1 requires interaction between Mcl-1 and BimFoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1Development, migration, and survival of mast cellsJNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosisAKT/PKB signaling: navigating downstreamThe Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signalingFoxo3a induces motoneuron death through the Fas pathway in cooperation with JNKFOXO transcription factors throughout T cell biologyFOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancerNeutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell linesThe Akt-regulated forkhead transcription factor FOXO3a controls endothelial cell viability through modulation of the caspase-8 inhibitor FLIPThe costimulation-regulated duration of PKB activation controls T cell longevityFKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cellsViolacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cellsComprehensive mRNA expression profiling distinguishes tauopathies and identifies shared molecular pathwaysAS101 prevents diabetic nephropathy progression and mesangial cell dysfunction: regulation of the AKT downstream pathwayTranscription factor Foxo3a prevents apoptosis by regulating calcium through the apoptosis repressor with caspase recruitment domainNerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylationPancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.Pleiotropic effects of PI-3' kinase/Akt signaling in human hepatoma cell proliferation and drug-induced apoptosis.Akt1 in osteoblasts and osteoclasts controls bone remodeling.Interleukin-7 regulates Bim proapoptotic activity in peripheral T-cell survival.Mitochondrial and postmitochondrial survival signaling in cancer.Bim, Bak, and Bax regulate osteoblast survival.Fish oil targets PTEN to regulate NFkappaB for downregulation of anti-apoptotic genes in breast tumor growth.Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells.Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cellsIntegrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cellsResveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors.Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.FOXO3 regulates CD8 T cell memory by T cell-intrinsic mechanisms.Hyperthermia induces apoptosis through endoplasmic reticulum and reactive oxygen species in human osteosarcoma cells.Highly specialized role of Forkhead box O transcription factors in the immune system.Sensing the environment: a historical perspective on integrin signal transduction.Infection of human coronary artery endothelial cells by group B streptococcus contributes to dysregulation of apoptosis, hemostasis, and innate immune responses
P2860
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P2860
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
FKHR-L1 can act as a critical ...... ce of mitochondrial integrity.
@ast
FKHR-L1 can act as a critical ...... ce of mitochondrial integrity.
@en
type
label
FKHR-L1 can act as a critical ...... ce of mitochondrial integrity.
@ast
FKHR-L1 can act as a critical ...... ce of mitochondrial integrity.
@en
prefLabel
FKHR-L1 can act as a critical ...... ce of mitochondrial integrity.
@ast
FKHR-L1 can act as a critical ...... ce of mitochondrial integrity.
@en
P2093
P2860
P356
P1476
FKHR-L1 can act as a critical ...... ce of mitochondrial integrity.
@en
P2093
Jan-Willem J Lammers
Kim U Birkenkamp
N Shaun B Thomas
Pascale F Dijkers
Paul J Coffer
P2860
P304
P356
10.1083/JCB.200108084
P407
P577
2002-01-28T00:00:00Z