Decreased exploratory activity in a mouse model of 15q duplication syndrome; implications for disturbance of serotonin signaling.
about
CNVs: harbingers of a rare variant revolution in psychiatric geneticsMice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autismCopy number variation at 22q11.2: from rare variants to common mechanisms of developmental neuropsychiatric disorders.Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficitsRelaxin-3-deficient mice showed slight alteration in anxiety-related behavior.Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism.Contextual and cued fear conditioning test using a video analyzing system in mice.Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of actionAnimal models of psychiatric disorders that reflect human copy number variation.Microbial communities in the upper respiratory tract of patients with asthma and chronic obstructive pulmonary diseaseAltered serotonin, dopamine and norepinepherine levels in 15q duplication and Angelman syndrome mouse modelsThe neurobiology of mouse models syntenic to human chromosome 15q.Cerebellar associative sensory learning defects in five mouse autism models.Variation in Dube3a expression affects neurotransmission at the Drosophila neuromuscular junction.Impaired burrowing is the most prominent behavioral deficit of aging htau mice.Mouse models of mutations and variations in autism spectrum disorder-associated genes: mice expressing Caps2/Cadps2 copy number and alternative splicing variants.New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain.Habituation of exploratory behaviour in VPA rats: animal model of autism.Distinct Defects in Spine Formation or Pruning in Two Gene Duplication Mouse Models of Autism.Modelling the genetic contribution to mental illness: a timely end for the psychiatric rodent?What Gene Mutations Affect Serotonin in Mice?Autism spectrum disorder model mice: Focus on copy number variation and epigenetics.The complex genetics in autism spectrum disorders.Using hiPSCs to model neuropsychiatric copy number variations (CNVs) has potential to reveal underlying disease mechanisms.Endothelial ErbB4 deficit induces alterations in exploratory behavior and brain energy metabolism in mice.Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism.Transcriptome profiling of white adipose tissue in a mouse model for 15q duplication syndrome.Comprehensive Behavioral Analysis of Activating Transcription Factor 5-Deficient Mice.Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice.Mice lacking the chromodomain helicase DNA-binding 5 chromatin remodeler display autism-like characteristics.Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication.Critical Reappraisal of Mechanistic Links of Copy Number Variants to Dimensional Constructs of Neuropsychiatric Disorders in Mouse Models.Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain.Rodent models of genetic and chromosomal variations in psychiatric disorders.Neuroanatomical Phenotypes Are Consistent With Autism-Like Behavioral Phenotypes in the 15q11-13 Duplication Mouse Model.Autistic disorder phenotype associated to a complex 15q intrachromosomal rearrangement.Common Defects of Spine Dynamics and Circuit Function in Neurodevelopmental Disorders: A Systematic Review of Findings From in Vivo Optical Imaging of Mouse Models.Juvenile stress induces behavioral change and affects perineuronal net formation in juvenile mice.Deletion of Long Isoform of Eukaryotic Elongation Factor 1Bδ Leads to Audiogenic Seizures and Aversive Stimulus-Induced Long-Lasting Activity Suppression in MiceCritical roles of serotonin-oxytocin interaction during the neonatal period in social behavior in 15q dup mice with autistic traits
P2860
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P2860
Decreased exploratory activity in a mouse model of 15q duplication syndrome; implications for disturbance of serotonin signaling.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Decreased exploratory activity ...... rbance of serotonin signaling.
@ast
Decreased exploratory activity ...... rbance of serotonin signaling.
@en
type
label
Decreased exploratory activity ...... rbance of serotonin signaling.
@ast
Decreased exploratory activity ...... rbance of serotonin signaling.
@en
prefLabel
Decreased exploratory activity ...... rbance of serotonin signaling.
@ast
Decreased exploratory activity ...... rbance of serotonin signaling.
@en
P2093
P2860
P50
P1433
P1476
Decreased exploratory activity ...... rbance of serotonin signaling.
@en
P2093
Fumiyuki Hatanaka
Jin Nakatani
Kota Tamada
Nobuhiro Nakai
Toru Takumi
P2860
P304
P356
10.1371/JOURNAL.PONE.0015126
P407
P577
2010-12-15T00:00:00Z