Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter
about
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferationInsights into granulosa cell tumors using spontaneous or genetically engineered mouse modelsJust how conserved is vertebrate sex determination?The disparate origins of ovarian cancers: pathogenesis and prevention strategies.FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development.Adult granulosa cell tumors of the ovary: a retrospective study of 30 cases with respect to the expression of steroid synthesis enzymes.Clinical and genetic analysis of recurrent adult-type granulosa cell tumor of the ovary: Persistent preservation of heterozygous c.402C>G FOXL2 mutation.Novel action of FOXL2 as mediator of Col1a2 gene autoregulation.The transcriptional targets of mutant FOXL2 in granulosa cell tumours.Molecular cloning and analysis of gonadal expression of Foxl2 in the rice-field eel Monopterus albusThe genetic make-up of ovarian development and function: the focus on the transcription factor FOXL2.Overexpression of wild-type but not C134W mutant FOXL2 enhances GnRH-induced cell apoptosis by increasing GnRH receptor expression in human granulosa cell tumors.Gonad differentiation in the rabbit: evidence of species-specific featuresEpigenetic control of gonadal aromatase (cyp19a1) in temperature-dependent sex determination of red-eared slider turtles.Overexpression of aromatase alone is sufficient for ovarian development in genetically male chicken embryosMolecular mechanisms of enhancing porcine granulosa cell proliferation and function by treatment in vitro with anti-inhibin alpha subunit antibody.17β-estradiol inhibits spreading of metastatic cells from granulosa cell tumors through a non-genomic mechanism involving GPER1Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis.A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticusMinireview: animal models and mechanisms of ovarian cancer development.Retreatment with aromatase inhibitor therapy in the management of granulosa cell tumor.Granulosa cell tumor mutant FOXL2C134W suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cellsFOXL2, GATA4, and SMAD3 co-operatively modulate gene expression, cell viability and apoptosis in ovarian granulosa cell tumor cells.Telling the story of XX sex reversal in the goat: highlighting the sex-crossroad in domestic mammals.The potential role of microRNAs in regulating gonadal sex differentiation in the chicken embryo.The molecular genetics of ovarian differentiation in the avian model.The molecular genetics of avian sex determination and its manipulation.Genetic changes in nonepithelial ovarian cancer.Understanding follicle growth in vitro: Are we getting closer to obtaining mature oocytes from in vitro-grown follicles in human?Adult ovarian granulosa cell tumor transcriptomics: prevalence of FOXL2 target genes misregulation gives insights into the pathogenic mechanism of the p.Cys134Trp somatic mutation.Aromatase P450 expression in human pituitary adenomas.Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary.FOXL2 posttranslational modifications mediated by GSK3β determine the growth of granulosa cell tumours.The Emerging Role of FOXL2 in Regulating the Transcriptional Activation Function of Estrogen Receptor β: An Insight Into Ovarian Folliculogenesis.Endogenous c-Jun N-terminal kinase (JNK) activity marks the boundary between normal and malignant granulosa cells.Logical modelling uncovers developmental constraints for primary sex determination of chicken gonads.Association between diabetes mellitus and progression free survival in women with ovarian granulosa cell tumors
P2860
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P2860
Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Aromatase is a direct target o ...... the ovarian specific promoter
@ast
Aromatase is a direct target o ...... the ovarian specific promoter
@en
type
label
Aromatase is a direct target o ...... the ovarian specific promoter
@ast
Aromatase is a direct target o ...... the ovarian specific promoter
@en
prefLabel
Aromatase is a direct target o ...... the ovarian specific promoter
@ast
Aromatase is a direct target o ...... the ovarian specific promoter
@en
P2093
P2860
P1433
P1476
Aromatase is a direct target o ...... the ovarian specific promoter
@en
P2093
Colin D Clyne
Evan R Simpson
Kevin C Knower
Kyren A Lazarus
Nicholas I Fleming
P2860
P304
P356
10.1371/JOURNAL.PONE.0014389
P407
P577
2010-12-20T00:00:00Z