STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes - Test2 - elhamkhani - TriplyDB

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes

http://www.wikidata.org/entity/Q33784496

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Genomic views of STAT function in CD4+ T helper cell differentiation Treg functional stability and its responsiveness to the microenvironment NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma The natural chemopreventive agent sulforaphane inhibits STAT5 activity Protein tyrosine phosphatases in the JAK/STAT pathway Phosphorylation of RelA/p65 promotes DNMT-1 recruitment to chromatin and represses transcription of the tumor metastasis suppressor gene BRMS1.Epigenetics in human autoimmunity. Epigenetics in autoimmunity - DNA methylation in systemic lupus erythematosus and beyond.Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.IL-6 signaling in psoriasis prevents immune suppression by regulatory T cells.Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1.DNA methylation of cancer genome.Lack of expression of inhibitory KIR3DL1 receptor in patients with natural killer cell-type lymphoproliferative disease of granular lymphocytes Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation.ALK-driven tumors and targeted therapy: focus on crizotinib Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression.Hypomethylation of CD30 CpG islands with aberrant JunB expression drives CD30 induction in Hodgkin lymphoma and anaplastic large cell lymphoma.A requirement of STAT3 DNA binding precludes Th-1 immunostimulatory gene expression by NF-κB in tumors.Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway.IL-2R common gamma-chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (NPM-ALK) and acts as a tumor suppressor by targeting NPM-ALK.Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling.Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells Targeting the interleukin-6/Jak/stat pathway in human malignancies Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoprotein Role of STAT3 in lung cancer.Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth The Drosophila BCL6 homolog Ken and Barbie promotes somatic stem cell self-renewal in the testis niche.Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma Promoter-specific induction of the phosphatase SHP-1 by viral infection and cytokines in CNS glia Epigenetic regulation of signal transducer and activator of transcription 3 in acute myeloid leukemia Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma.Targeting the PTPome in human disease.Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts G-CSF-activated STAT3 enhances production of the chemokine MIP-2 in bone marrow neutrophils.Protein-tyrosine phosphatases and cancer.The role of Janus kinases in haemopoiesis and haematological malignancy.Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain SOCS3 promotor hypermethylation and STAT3-NF-κB interaction downregulate SOCS3 expression in human coronary artery smooth muscle cells.

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STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes

http://www.wikidata.org/entity/Q33784496

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2005 nî lūn-bûn

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STAT3- and DNA methyltransfera ...... ene in malignant T lymphocytes

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STAT3- and DNA methyltransfera ...... ene in malignant T lymphocytes

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STAT3- and DNA methyltransfera ...... ene in malignant T lymphocytes

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STAT3- and DNA methyltransfera ...... ene in malignant T lymphocytes

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STAT3- and DNA methyltransfera ...... ene in malignant T lymphocytes

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STAT3- and DNA methyltransfera ...... ene in malignant T lymphocytes

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Proceedings of the National Academy of Sciences of the United States of America

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STAT3- and DNA methyltransfera ...... ene in malignant T lymphocytes

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Hong Y Wang

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Mariusz A Wasik

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Michal Marzec

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Puthiyaveettil N Raghunath

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Qian Zhang

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Tomohiko Nagasawa

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P2860

The fundamental role of epigenetic events in cancer

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

Stat protein transactivation domains recruit p300/CBP through widely divergent sequences

A road map for those who don't know JAK-STAT

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites

The STATs of cancer--new molecular targets come of age

Gene silencing in cancer in association with promoter hypermethylation

CREB-binding protein and p300: molecular integrators of hematopoietic transcription.

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