Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
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The basal transcription machinery as a target for cancer therapyCaspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loopSuppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapyPreclinical Murine Models for Lung Cancer: Clinical Trial ApplicationsThe PIDDosome, DNA-damage-induced apoptosis and beyondBlocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer.Detoxifying antitumoral drugs via nanoconjugation: the case of gold nanoparticles and cisplatinHistological changes in kidney and liver of rats due to gold (III) compound [Au(en)Cl(2)]ClComputed tomography imaging of primary lung cancer in mice using a liposomal-iodinated contrast agentTherapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer.Up-regulation of miR-146a increases the sensitivity of non-small cell lung cancer to DDP by downregulating cyclin J.DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways.Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways.Integrated genomics of ovarian xenograft tumor progression and chemotherapy response.Small RNA combination therapy for lung cancerChronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma.Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance.Residual tumor cells that drive disease relapse after chemotherapy do not have enhanced tumor initiating capacity.Growth pattern analysis of murine lung neoplasms by advanced semi-automated quantification of micro-CT images.Expression of DNA translesion synthesis polymerase η in head and neck squamous cell cancer predicts resistance to gemcitabine and cisplatin-based chemotherapy.Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo.Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLCCompromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.NCI's provocative questions on cancer: some answers to ignite discussion.Generation of primary tumors with Flp recombinase in FRT-flanked p53 miceSynthesis, aqueous reactivity, and biological evaluation of carboxylic acid ester-functionalized platinum-acridine hybrid anticancer agents.IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated moleculesHuman lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivityInhibition of Myc family proteins eradicates KRas-driven lung cancer in miceAssessing the radiation response of lung cancer with different gene mutations using genetically engineered mice.Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burdenDNA repair capacity in peripheral lymphocytes predicts survival of patients with non-small-cell lung cancer treated with first-line platinum-based chemotherapy.Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy.How genetically engineered mouse tumor models provide insights into human cancersOncogenic miR-137 contributes to cisplatin resistance via repressing CASP3 in lung adenocarcinoma.Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumour cells and response to platinum treatment.Hepatocellular carcinoma stem cell-like cells are enriched following low-dose 5-fluorouracil chemotherapy.NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer.Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.
P2860
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P2860
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Chronic cisplatin treatment pr ...... n a mouse model of lung cancer
@ast
Chronic cisplatin treatment pr ...... n a mouse model of lung cancer
@en
type
label
Chronic cisplatin treatment pr ...... n a mouse model of lung cancer
@ast
Chronic cisplatin treatment pr ...... n a mouse model of lung cancer
@en
prefLabel
Chronic cisplatin treatment pr ...... n a mouse model of lung cancer
@ast
Chronic cisplatin treatment pr ...... n a mouse model of lung cancer
@en
P2093
P2860
P50
P356
P1433
P1476
Chronic cisplatin treatment pr ...... n a mouse model of lung cancer
@en
P2093
Aravind Subramanian
Arjun Bhutkar
Charles A Whittaker
Denise Crowley
Diana Mendus
E Alejandro Sweet-Cordero
James R Burke
Juergen Thomale
Kim L Mercer
Leanne C Sayles
P2860
P304
P356
10.1101/GAD.1897010
P577
2010-04-01T00:00:00Z