Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. - Test2 - elhamkhani - TriplyDB

Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.

Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.

http://www.wikidata.org/entity/Q33796016

about

A proteomic characterization of factors enriched at nascent DNA molecules The Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like Modifiers Role of Deubiquitinating Enzymes in DNA Repair Predisposition to cancer caused by genetic and functional defects of mammalian Atad5 Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.The DNA Damage Response: Making It Safe to Play with Knives DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity.Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteins WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1)Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance ATAD5 deficiency decreases B cell division and Igh recombination A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors Managing missing measurements in small-molecule screens.Dynamic regulation of PCNA ubiquitylation/deubiquitylation.Regulation of the Fanconi anemia pathway by a SUMO-like delivery network Identification of six new susceptibility loci for invasive epithelial ovarian cancer.Relevance of simultaneous mono-ubiquitinations of multiple units of PCNA homo-trimers in DNA damage tolerance.Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype Artificial Recruitment of UAF1-USP Complexes by a PHLPP1-E1 Chimeric Helicase Enhances Human Papillomavirus DNA Replication.High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.The nucleosome binding protein HMGN1 interacts with PCNA and facilitates its binding to chromatin.K63-linked ubiquitination in kinase activation and cancer.Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma.ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin.The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition Ubiquitylation and the Fanconi anemia pathway.Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?The WD40-repeat protein-containing deubiquitinase complex: catalysis, regulation, and potential for therapeutic intervention.Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity.Emerging genotype-phenotype relationships in patients with large NF1 deletions.Ubiquitin-family modifications in the replication of DNA damage.Ub-family modifications at the replication fork: Regulating PCNA-interacting components.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Readers of PCNA modifications Deubiquitylases from genes to organism.

P2860

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P2860

Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.

http://www.wikidata.org/entity/Q33796016

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Human ELG1 regulates the level ...... teractions with PCNA and USP1.

@ast

Human ELG1 regulates the level ...... teractions with PCNA and USP1.

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type

label

Human ELG1 regulates the level ...... teractions with PCNA and USP1.

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Human ELG1 regulates the level ...... teractions with PCNA and USP1.

@en

prefLabel

Human ELG1 regulates the level ...... teractions with PCNA and USP1.

@ast

Human ELG1 regulates the level ...... teractions with PCNA and USP1.

@en

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JBC.M109.092544

P1433

Journal of Biological Chemistry

P1476

Human ELG1 regulates the level ...... teractions with PCNA and USP1.

@en

P2093

Alan D D'Andrea

http://www.w3.org/2001/XMLSchema#string

Kyoo-Young Lee

http://www.w3.org/2001/XMLSchema#string

Kyungjae Myung

http://www.w3.org/2001/XMLSchema#string

Nilabja Sikdar

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P2860

CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork

Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin

A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway

Tyrosine phosphorylation controls PCNA function through protein stability

UAF1 is a subunit of multiple deubiquitinating enzyme complexes

Purification and characterization of human DNA damage checkpoint Rad complexes

Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination

Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks

The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA

Elg1 forms an alternative RFC complex important for DNA replication and genome integrity

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scholarly article

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20147293

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protein ubiquitination

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2856242

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