Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
about
Spartan/C1orf124 is important to prevent UV-induced mutagenesisProliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesisCBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesisDNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchangeZRANB3 is a structure-specific ATP-dependent endonuclease involved in replication stress responseThe Role of PCNA Posttranslational Modifications in Translesion SynthesisUbc13: the Lys63 ubiquitin chain building machineThe Regulation of DNA Damage Tolerance by Ubiquitin and Ubiquitin-Like ModifiersFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressHelicase-like transcription factor (Hltf) regulates G2/M transition, Wt1/Gata4/Hif-1a cardiac transcription networks, and collagen biogenesisPHD domain from human SHPRHPhysical and genetic associations of the Irc20 ubiquitin ligase with Cdc48 and SUMO.Replication stress: getting back on trackBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Regulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteinsRAD51 mutants cause replication defects and chromosomal instabilityDNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesisCharacterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage toleranceSHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis.Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site LevelIndividual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation.Structure of a Novel DNA-binding Domain of Helicase-like Transcription Factor (HLTF) and Its Functional Implication in DNA Damage ToleranceVisualisation of PCNA monoubiquitination in vivo by single pass spectral imaging FRET microscopy.Regulation of PCNA polyubiquitination in human cells.Role of double-stranded DNA translocase activity of human HLTF in replication of damaged DNAHuman ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.Multiple Rad5 activities mediate sister chromatid recombination to bypass DNA damage at stalled replication forks.Coordinated protein and DNA remodeling by human HLTF on stalled replication forkDeletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forksHuman DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma.Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomesATP-dependent chromatin remodeling: genetics, genomics and mechanisms.Role of helicase-like transcription factor (hltf) in the G2/m transition and apoptosis in brain.Clearance of roadblocks in replication fork restart.Crosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistanceDynamic regulation of PCNA ubiquitylation/deubiquitylation.A novel ubiquitin binding mode in the S. cerevisiae translesion synthesis DNA polymerase ηATP-dependent chromatin remodeling in the DNA-damage response.
P2860
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P2860
Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Polyubiquitination of prolifer ...... from stalled replication forks
@ast
Polyubiquitination of prolifer ...... from stalled replication forks
@en
Polyubiquitination of prolifer ...... from stalled replication forks
@nl
type
label
Polyubiquitination of prolifer ...... from stalled replication forks
@ast
Polyubiquitination of prolifer ...... from stalled replication forks
@en
Polyubiquitination of prolifer ...... from stalled replication forks
@nl
prefLabel
Polyubiquitination of prolifer ...... from stalled replication forks
@ast
Polyubiquitination of prolifer ...... from stalled replication forks
@en
Polyubiquitination of prolifer ...... from stalled replication forks
@nl
P2093
P2860
P921
P3181
P356
P1476
Polyubiquitination of prolifer ...... from stalled replication forks
@en
P2093
Akira Motegi
Helen Moinova
Henk P Roest
Jan H J Hoeijmakers
Kyoo-Young Lee
Kyungjae Myung
Sanford D Markowitz
P2860
P304
12411-12416
P3181
P356
10.1073/PNAS.0805685105
P407
P577
2008-08-21T00:00:00Z