Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants. - Test2 - elhamkhani - TriplyDB

Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants.

Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants.

http://www.wikidata.org/entity/Q33803840

about

Breaking the Spell: Combating Multidrug Resistant 'Superbugs'Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin Antibiotics for emerging pathogens Discovering antibiotic efficacy biomarkers: toward mechanism-specific high content compound screening.The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications.The transcriptional response of Pasteurella multocida to three classes of antibiotics Postgenomic strategies in antibacterial drug discovery.Challenges of antibacterial discovery Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus.Novel bacterial acetyl coenzyme A carboxylase inhibitors with antibiotic efficacy in vivo.Genetic Approaches to Facilitate Antibacterial Drug Development.Inhibiting bacterial fatty acid synthesis.Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252.Andrimid producers encode an acetyl-CoA carboxyltransferase subunit resistant to the action of the antibiotic.Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules Cellular reporter screens for inhibitors of Burkholderia pseudomallei targets in Pseudomonas aeruginosa Application of bacterial cytological profiling to crude natural product extracts reveals the antibacterial arsenal of Bacillus subtilis.Using genomics to develop novel antibacterial therapeutics.Proteomic signatures in antibiotic research.Engineered cells as biosensing systems in biomedical analysis.Asymmetric organocatalytic addition reactions of maleimides: a promising approach towards the synthesis of chiral succinimide derivatives.New trends in peptide-based anti-biofilm strategies: a review of recent achievements and bioinformatic approaches.Using 'omic' technology to target Helicobacter pylori.Phenotypic profiling of antibiotic response signatures in Escherichia coli using Raman spectroscopy.Strategies for target identification of antimicrobial natural products.Transcriptomics as a tool to discover new antibacterial targets.The Potential of Systems Biology to Discover Antibacterial Mechanisms of Plant Phenolics.Novel whole-cell antibiotic biosensors for compound discovery.A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid.Global analysis of the Staphylococcus aureus response to mupirocin.Transcriptional signature following inhibition of early-stage cell wall biosynthesis in Staphylococcus aureus.Global transcriptional responses of Bacillus subtilis to xenocoumacin 1.A disk-diffusion-based target identification platform for antibacterials (TIPA): an inducible assay for profiling MOAs of antibacterial compounds.Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.Main antimicrobial components of Tinospora capillipes, and their mode of action against Staphylococcus aureus.Organocatalytic asymmetric Michael addition of α-alkylidene succinimides to nitrostyrenes.Highly enantioselective Michael addition promoted by a new diterpene-derived bifunctional thiourea catalyst: a doubly stereocontrolled approach to chiral succinimide derivatives.

P2860

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P2860

Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants.

http://www.wikidata.org/entity/Q33803840

description

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Antimicrobial Agents and Chemotherapy

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H P Fischer

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The COG database: an updated version includes eukaryotes

Genome wide identification of regulatory motifs in Bacillus subtilis

Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

Transcriptional regulation and signature patterns revealed by microarray analyses of Streptococcus pneumoniae R6 challenged with sublethal concentrations of translation inhibitors

Gene expression changes triggered by exposure of Haemophilus influenzae to novobiocin or ciprofloxacin: combined transcription and translation analysis

Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis

Multiclass cancer diagnosis using tumor gene expression signatures

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

DBTBS: a database of Bacillus subtilis promoters and transcription factors.

Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics.

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