about
When Quality Beats Quantity: Decision Theory, Drug Discovery, and the Reproducibility CrisisTackling the threat of antimicrobial resistance: from policy to sustainable actionStructural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall BiogenesisWhole-genome sequencing targets drug-resistant bacterial infectionsResistance to antibiotics targeted to the bacterial cell wallThere should be no ESKAPE for febrile neutropenic cancer patients: the dearth of effective antibacterial drugs threatens anticancer efficacyA Molecularly Complete Planar Bacterial Outer Membrane PlatformLearning from the past for TB drug discovery in the futureInhibition of Bacterial Dihydrofolate Reductase by 6-Alkyl-2,4-diaminopyrimidinesIn Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzaeRestoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibioticsDiscovery of Inhibitors of 4'-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial TherapyStructural Basis for the Recognition of Mycolic Acid Precursors by KasA, a Condensing Enzyme and Drug Target from Mycobacterium TuberculosisAn aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding modeThe Structure and Competitive Substrate Inhibition of Dihydrofolate Reductase from Enterococcus faecalis Reveal Restrictions to Cofactor DockingRational Design of Broad Spectrum Antibacterial Activity Based on a Clinically Relevant Enoyl-Acyl Carrier Protein (ACP) Reductase InhibitorHoney in the Prevention and Treatment of Infection in the CKD Population: A Narrative ReviewResistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) AntibioticsBacterial cell biology outside the streetlightMorphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of actionIndole trimers with antibacterial activity against Gram-positive organisms produced using combinatorial biocatalysisNon-traditional antibacterial screening approaches for the identification of novel inhibitors of the glyoxylate shunt in gram-negative pathogensLipophilic prodrugs of FR900098 are antimicrobial against Francisella novicida in vivo and in vitro and show GlpT independent efficacyProtein interactions in genome maintenance as novel antibacterial targetsCharacterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosisTricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agentsWhole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureusRepurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureusAn IPTG Inducible Conditional Expression System for MycobacteriaSteering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic ResistanceCrystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement RevisitedTargeting an Essential GTPase Obg for the Development of Broad-Spectrum AntibioticsOminous projections for global antibiotic use in food-animal productionResistance-resistant antibioticsEndless Resistance. Endless Antibiotics?Antimicrobial resistance-a threat to the world's sustainable developmentSynthesis and Antimicrobial Evaluation of Amixicile-Based Inhibitors of the Pyruvate-Ferredoxin Oxidoreductases of Anaerobic Bacteria and Epsilonproteobacteria.Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.A novel high-throughput cell-based assay aimed at identifying inhibitors of DNA metabolism in bacteriaArt-175 is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Challenges of antibacterial discovery
@ast
Challenges of antibacterial discovery
@en
type
label
Challenges of antibacterial discovery
@ast
Challenges of antibacterial discovery
@en
prefLabel
Challenges of antibacterial discovery
@ast
Challenges of antibacterial discovery
@en
P2860
P356
P1476
Challenges of antibacterial discovery
@en
P2093
Lynn L Silver
P2860
P304
P356
10.1128/CMR.00030-10
P407
P577
2011-01-01T00:00:00Z