Cdk5 nuclear localization is p27-dependent in nerve cells: implications for cell cycle suppression and caspase-3 activation.
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A Unified Hypothesis of Early- and Late-Onset Alzheimer's Disease PathogenesisThe endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive diseaseTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsMechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disordersNuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal deathCDK5 activator protein p25 preferentially binds and activates GSK3βModulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease.Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis.Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neuronsThe roles of Cdk5-mediated subcellular localization of FOXO1 in neuronal death.Cdk5 levels oscillate during the neuronal cell cycle: Cdh1 ubiquitination triggers proteosome-dependent degradation during S-phase.Alteration of Golgi Structure by Stress: A Link to Neurodegeneration?Low Expression of CDK5 and p27 Are Associated with Poor Prognosis in Patients with Gastric Cancer.Stress-induced nuclear translocation of CDK5 suppresses neuronal death by downregulating ERK activation via VRK3 phosphorylation.MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neuronsCyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulationExpression of CRM1 and CDK5 shows high prognostic accuracy for gastric cancer.Cell cycle reactivation in mature neurons: a link with brain plasticity, neuronal injury and neurodegenerative diseases?Regulation of sirtuin function by posttranslational modificationsp27Kip1 inhibits the cell cycle through non-canonical G1/S phase-specific gatekeeper mechanism.Cdk5: An Emerging Kinase in Pain SignalingAbortive cell cycle events in the brains of scrapie-infected hamsters with remarkable decreases of PLK3/Cdc25C and increases of PLK1/cyclin B1.Herpes simplex virus 1 upregulates p35, alters CDK-5 localization, and stimulates CDK-5 kinase activity during acute infection in neurons.Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex.Role of a cdk5-associated protein, p35, in herpes simplex virus type 1 replication in vivo.Role and regulation of p27 in neuronal apoptosis.Nucleocytoplasmic p27Kip1 Export Is Required for ERK1/2-Mediated Reactive Astroglial Proliferation Following Status Epilepticus.Cyclin-dependent kinase 5-mediated phosphorylation of chloride intracellular channel 4 promotes oxidative stress-induced neuronal death
P2860
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P2860
Cdk5 nuclear localization is p27-dependent in nerve cells: implications for cell cycle suppression and caspase-3 activation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cdk5 nuclear localization is p ...... sion and caspase-3 activation.
@ast
Cdk5 nuclear localization is p ...... sion and caspase-3 activation.
@en
type
label
Cdk5 nuclear localization is p ...... sion and caspase-3 activation.
@ast
Cdk5 nuclear localization is p ...... sion and caspase-3 activation.
@en
prefLabel
Cdk5 nuclear localization is p ...... sion and caspase-3 activation.
@ast
Cdk5 nuclear localization is p ...... sion and caspase-3 activation.
@en
P2093
P2860
P356
P1476
Cdk5 nuclear localization is p ...... sion and caspase-3 activation.
@en
P2093
Huifang Li
Karl Herrup
P2860
P304
14052-14061
P356
10.1074/JBC.M109.068262
P407
P577
2010-02-26T00:00:00Z