A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.
about
Plant and animal pathogen recognition receptors signal through non-RD kinasesThe cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replicationShp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cellsC-terminal phosphorylation controls the stability and function of p27kip114-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machineryA NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisU2AF homology motifs: protein recognition in the RRM worldTransforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor proteinDeregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerRegulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"Protein kinase KIS localizes to RNA granules and enhances local translationSuccessive phosphorylation of p27(KIP1) protein at serine-10 and C terminus crucially controls its potency to inactivate Cdk2Signaling from the secretory granule to the nucleus: Uhmk1 and PAMCalpain activation is required for glutamate-induced p27 down-regulation in cultured cortical neuronsTetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinomaPCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.Maternal nutrient restriction alters gene expression in the ovine fetal heart.p27Kip1 localization depends on the tumor suppressor protein tuberin.p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation.Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.EGFR/HER2 inhibitor AEE788 increases ER-mediated transcription in HER2/ER-positive breast cancer cells but functions synergistically with endocrine therapy.Cdk5 nuclear localization is p27-dependent in nerve cells: implications for cell cycle suppression and caspase-3 activation.The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiationThe role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cellsThe impact of CDK inhibition in human malignancies associated with pronounced defects in apoptosis: advantages of multi-targeting small molecules.A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppressionA novel role of proteasomal β1 subunit in tumorigenesis.Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice.Phosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cellsp27: a barometer of signaling deregulation and potential predictor of response to targeted therapies.BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein.PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser¹⁰ p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer.Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical regionComplex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localizationRegulation of CDK4
P2860
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P248
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P2860
A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A growth factor-dependent nucl ...... gulates cell cycle progression
@nl
A growth factor-dependent nucl ...... ulates cell cycle progression.
@ast
A growth factor-dependent nucl ...... ulates cell cycle progression.
@en
A growth factor-dependent nucl ...... ulates cell cycle progression.
@en-gb
type
label
A growth factor-dependent nucl ...... gulates cell cycle progression
@nl
A growth factor-dependent nucl ...... ulates cell cycle progression.
@ast
A growth factor-dependent nucl ...... ulates cell cycle progression.
@en
A growth factor-dependent nucl ...... ulates cell cycle progression.
@en-gb
prefLabel
A growth factor-dependent nucl ...... gulates cell cycle progression
@nl
A growth factor-dependent nucl ...... ulates cell cycle progression.
@ast
A growth factor-dependent nucl ...... ulates cell cycle progression.
@en
A growth factor-dependent nucl ...... ulates cell cycle progression.
@en-gb
P2093
P2860
P921
P3181
P356
P1433
P1476
A growth factor-dependent nucl ...... ulates cell cycle progression.
@en
P2093
Andrea True
Elizabeth G Nabel
Manfred Boehm
Martin F Crook
Shriram Nallamshetty
Takanobu Yoshimoto
P2860
P304
P3181
P356
10.1093/EMBOJ/CDF343
P407
P50
P577
2002-07-01T00:00:00Z