HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. - Test2 - elhamkhani - TriplyDB

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

http://www.wikidata.org/entity/Q33815755

about

BRCA1 is a negative modulator of the PRC2 complex Data Mining Approaches for Genomic Biomarker Development: Applications Using Drug Screening Data from the Cancer Genome Project and the Cancer Cell Line Encyclopedia Fighting the force: Potential of homeobox genes for tumor microenvironment regulation The Pbx interaction motif of Hoxa1 is essential for its oncogenic activity BRCA1: linking HOX to breast cancer suppression miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10.ECM stiffness paves the way for tumor cells.Growth and differentiation factor 3 induces expression of genes related to differentiation in a model of cancer stem cells and protects them from retinoic acid-induced apoptosis.Engineering a stem cell house into a home NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva.Investigation of HOXA9 promoter methylation as a biomarker to distinguish oral cancer patients at low risk of neck metastasis.Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance.Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells.HOXB5 Promotes the Proliferation and Invasion of Breast Cancer Cells.The role of components of the chromatin modification machinery in carcinogenesis of clear cell carcinoma of the ovary (Review)HOXA9 promotes ovarian cancer growth by stimulating cancer-associated fibroblasts.Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression.β3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner HOXC9 Induces Phenotypic Switching between Proliferation and Invasion in Breast Cancer Cells.HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.The function of homeobox genes and lncRNAs in cancer.An Epigenomic Approach to Improving Response to Neoadjuvant Cisplatin Chemotherapy in Bladder Cancer Biomarkers for Basal-like Breast Cancer.Expression of the homeobox gene HOXA9 in ovarian cancer induces peritoneal macrophages to acquire an M2 tumor-promoting phenotype.Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells Cancer dormancy: time to explore its clinical relevance.Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.The dual roles of homeobox genes in vascularization and wound healing.Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin.Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease.The roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC).HOXA9 inhibits migration of lung cancer cells and its hypermethylation is associated with recurrence in non-small cell lung cancer.Characterization of HOX gene expression in canine mammary tumour cell lines from spontaneous tumours.Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation.EZH2 and histone deacetylase inhibitors induce apoptosis in triple negative breast cancer cells by differentially increasing H3 Lys27 acetylation in the BIM gene promoter and enhancers.Analysis of HOX gene expression patterns in human breast cancer.The role of Rak in the regulation of stability and function of BRCA1.High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis.Overexpression of HOXA4 and HOXA9 genes promotes self-renewal and contributes to colon cancer stem cell overpopulation.HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development.

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P2860

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

http://www.wikidata.org/entity/Q33815755

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

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HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

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type

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HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

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HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

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prefLabel

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

@ast

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

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Journal of Clinical Investigation

P1476

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype

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P2093

Alana L Welm

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Barbara L Weber

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Janna K Mouw

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Johnathon N Lakins

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Jonathan D Licht

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Kelvin K C Tsai

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Mawuse K Gbegnon

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Meredith A Unger

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Michael D Feldman

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Miriam Benezra

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P2860

DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

Compromised HOXA5 function can limit p53 expression in human breast tumours

Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach

HOXA5-twist interaction alters p53 homeostasis in breast cancer cells

TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins.

The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1

Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis

MicroRNA-126 regulates HOXA9 by binding to the homeobox

The epithelial-mesenchymal transition generates cells with properties of stem cells

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1535-1550

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10.1172/JCI39534

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5

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120

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Penney M Gilbert

Valerie M Weaver

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2010-04-12T00:00:00Z

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20389018

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2860938

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