Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells.
about
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humansDietary restriction with and without caloric restriction for healthy agingLongevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatinManipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels.Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae.The oncogenic RAS2(val19) mutation locks respiration, independently of PKA, in a mode prone to generate ROS.Six plant extracts delay yeast chronological aging through different signaling pathwaysFasting and differential chemotherapy protection in patientsFasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients."Sleeping beauty": quiescence in Saccharomyces cerevisiae.Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.SOD2 functions downstream of Sch9 to extend longevity in yeast.At the brink of eusociality: transcriptomic correlates of worker behaviour in a small carpenter beeTranscriptional regulation in yeast during diauxic shift and stationary phase.Signaling linkage between environmental stress resistance and leaf senescence in Arabidopsis.The Yeast GSK-3 Homologue Mck1 Is a Key Controller of Quiescence Entry and Chronological Lifespan.Conserved role of medium acidification in chronological senescence of yeast and mammalian cellsFunctional analyses of human DNA repair proteins important for aging and genomic stability using yeast geneticsAn Energy-Independent Pro-longevity Function of Triacylglycerol in YeastStarvation, detoxification, and multidrug resistance in cancer therapyCharacterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.Chronological aging-induced apoptosis in yeast.Iron-depletion promotes mitophagy to maintain mitochondrial integrity in pathogenic yeast Candida glabrataShort-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression.Mitochondrial SKN-1/Nrf mediates a conserved starvation response.Concentration-Dependent Effects of Rhodiola Rosea on Long-Term Survival and Stress Resistance of Yeast Saccharomyces Cerevisiae: The Involvement of YAP 1 and MSN2/4 Regulatory Proteins.Growth culture conditions and nutrient signaling modulating yeast chronological longevity.Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae.P62/SQSTM1 at the interface of aging, autophagy, and disease.Starvation response in mouse liver shows strong correlation with life-span-prolonging processes.Epigenetic Mechanisms of Longevity and Aging.DNA repair and mutations during quiescence in yeast.Protective effects of short-term dietary restriction in surgical stress and chemotherapy.Unbalanced Growth, Senescence and Aging.Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevityRole of Oxidative Stress Response and Trehalose Accumulation in the Longevity of Fission YeastMetabolites in aging and autophagy.Conserved role of Ras-GEFs in promoting aging: from yeast to mice.
P2860
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P2860
Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mutations in signal transducti ...... and mammalian neuronal cells.
@ast
Mutations in signal transducti ...... and mammalian neuronal cells.
@en
type
label
Mutations in signal transducti ...... and mammalian neuronal cells.
@ast
Mutations in signal transducti ...... and mammalian neuronal cells.
@en
prefLabel
Mutations in signal transducti ...... and mammalian neuronal cells.
@ast
Mutations in signal transducti ...... and mammalian neuronal cells.
@en
P1476
Mutations in signal transducti ...... and mammalian neuronal cells.
@en
P2093
P304
P356
10.1016/S0197-4580(99)00089-5
P577
1999-09-01T00:00:00Z